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In 1834, François Mothes and Joseph Dublanc created a method to produce a single-piece gelatin capsule that was sealed with a drop of gelatin solution. In 1853 Alexander Wood was the first physician that used hypodermic needle to dispense drugs via Injections. In 1858 Dr. M. Sales Giron invented the first pressurized inhaler.
Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) [1] was an American biochemist, broad researcher of synthetic psychoactive compounds, and author of works regarding these, who independently explored the organic chemistry and pharmacology of such agents—in his mid-life and later, many through preparation in his home laboratory, and testing on himself. [2]
In the fields of medicine, biotechnology, and pharmacology, drug discovery is the process by which new candidate medications are discovered. [1]Historically, drugs were discovered by identifying the active ingredient from traditional remedies or by serendipitous discovery, as with penicillin.
For example, in 1260 CE a Cairenes pharmacist named Abu ‘I-Munā al-Kuhín al-‘Attār published a 25-chapter manual, the Minhāj al-dukkān (How to run a pharmacy), wherein he documented: titles of drugs, their ingredients and quantities, preparation methods, and dosages. The manual noticeably lacks any chapters that highlight desirable ...
Working with his team, he developed the fentanyl family of drugs and a number of anesthetic agents, including droperidol and etomidate. [6] [7] One of the anti-diarrheal drugs he developed, diphenoxylate , was used in the Apollo program. [8] [9] In 1959, Janssen synthesized the potent opioid fentanyl based on SAR studies of meperidine.
Percy Lavon Julian (April 11, 1899 – April 19, 1975) was an American research chemist and a pioneer in the chemical synthesis of medicinal drugs from plants. [1] Julian was the first person to synthesize the natural product physostigmine, and a pioneer in industrial large-scale chemical synthesis of the human hormones progesterone and testosterone from plant sterols such as stigmasterol and ...
Albert Hofmann (11 January 1906 – 29 April 2008) was a Swiss chemist known for being the first to synthesize, ingest, and learn of the psychedelic effects of lysergic acid diethylamide (LSD).
Drugs.com is an online pharmaceutical encyclopedia that provides drug information for consumers and healthcare professionals, primarily in the United States. It self-describes its information as "accurate and independent" yet limited to being "for educational purposes only and is not intended for medical advice, diagnosis or treatment."