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  2. Genotoxicity - Wikipedia

    en.wikipedia.org/wiki/Genotoxicity

    Comfrey is an example of a plant species that contains fourteen different PAs. The active metabolites interact with DNA to cause DNA damage, mutation induction, and cancer development in liver endothelial cells and hepatocytes. The researchers discovered in the end that the "comfrey is mutagenic in liver, and PA contained in comfrey appear to ...

  3. Mutation - Wikipedia

    en.wikipedia.org/wiki/Mutation

    In humans, the mutation rate is about 50–90 de novo mutations per genome per generation, that is, each human accumulates about 50–90 novel mutations that were not present in his or her parents. This number has been established by sequencing thousands of human trios, that is, two parents and at least one child.

  4. Genetically modified animal - Wikipedia

    en.wikipedia.org/wiki/Genetically_modified_animal

    Principles such as animal integrity, naturalness, risk identification and animal welfare are examples of ethically important factors that must be taken into consideration, and they also influence public perception and regulatory decisions by authorities. [196] The utility of extrapolating animal data to humans has been questioned.

  5. Just one mutation can make H5N1 bird flu a threat to humans ...

    www.aol.com/news/just-one-mutation-h5n1-bird...

    Animals such as birds and humans have different docking stations on their cells — known as sialic acid receptors. In order for a flu virus to open a door into a cell and begin replicating, it ...

  6. Genetic pollution - Wikipedia

    en.wikipedia.org/wiki/Genetic_pollution

    Genetic pollution is a term for uncontrolled [1] [2] gene flow into wild populations. It is defined as "the dispersal of contaminated altered genes from genetically engineered organisms to natural organisms, esp. by cross-pollination", [3] but has come to be used in some broader ways.

  7. Germline mutation - Wikipedia

    en.wikipedia.org/wiki/Germline_mutation

    A germline mutation, or germinal mutation, is any detectable variation within germ cells (cells that, when fully developed, become sperm and ova). [1] Mutations in these cells are the only mutations that can be passed on to offspring, when either a mutated sperm or oocyte come together to form a zygote . [ 2 ]

  8. Key warning signs about bird flu are all going in the wrong ...

    www.aol.com/key-warning-signs-bird-flu-170000168...

    Among them are recent detections of the virus in wastewater and signs of dangerous mutations. ... It’s not possible to know if the virus fragments found came from animal or human sources. Some ...

  9. Lethal allele - Wikipedia

    en.wikipedia.org/wiki/Lethal_allele

    This is because the BRCA mutations also result in a severe subtype of Fanconi anemia (FA-S for BRCA1, FA-D1 for BRCA2), itself an extremely rare medical condition. Another example of a recessive lethal allele occurs in the Manx cat. Manx cats possess a heterozygous mutation resulting in a shortened or missing tail.