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These alterations at the DNA level may explain, at least in part, the impairments of cognitive function after chemotherapy. [11] Common side effects are ureteric obstruction (narrowing or blockage of the ureter that may lead to excess fluid in the kidney due to a backup of urine), flank pain (pain occurring on the side of the body), urinary ...
Data from 40 phase II and phase III studies with patients undergoing a one-hour infusion of 100 mg/m 2 docetaxel once every three weeks. Docetaxel is a cytotoxic chemotherapeutic agent. [12] [25] As with all chemotherapy, adverse effects are common, and many side effects have been documented.
Common side effects include bone marrow suppression, vomiting, diarrhea, liver problems, rash, ulcer formation in the mouth, and bleeding. [2] Other serious side effects include loss of consciousness, lung disease, and allergic reactions. [2] Use during pregnancy may harm the baby. [2]
Fluorouracil (5-FU, 5-fluorouracil), sold under the brand name Adrucil among others, is a cytotoxic chemotherapy medication used to treat cancer. [3] By intravenous injection it is used for treatment of colorectal cancer, oesophageal cancer, stomach cancer, pancreatic cancer, breast cancer, and cervical cancer. [3]
Common side effects include abdominal pain, vomiting, diarrhea, weakness, and rashes. [4] Other severe side effects include blood clotting problems, allergic reactions, heart problems such as cardiomyopathy, and low blood cell counts. [4] Use during pregnancy may result in harm to the fetus. [4]
Eribulin, sold under the brand name Halaven among others, is an anti-cancer medication used to treat breast cancer and liposarcoma. [4] [5]The most common side effects include fatigue, nausea, hair loss (alopecia), constipation, certain nerve damage causing weakness or numbness in the hands and feet (peripheral neuropathy), abdominal pain and fever (pyrexia). [10]
Cyclophosphamide is a pregnancy category D drug and causes birth defects. First trimester exposure to cyclophosphamide for the treatment of cancer or lupus displays a pattern of anomalies labeled "cyclophosphamide embryopathy", including growth restriction, ear and facial abnormalities, absence of digits and hypoplastic limbs. [17]
Gemcitabine is a chemotherapy drug that works by killing any cells that are dividing. [10] Cancer cells divide rapidly and so are targeted at higher rates by gemcitabine, but many essential cells also divide rapidly, including cells in skin, the scalp, the stomach lining, and bone marrow, resulting in adverse effects. [16]: 265
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