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The different stages of mitosis altogether define the mitotic phase (M phase) of a cell cycle—the division of the mother cell into two daughter cells genetically identical to each other. [3] The process of mitosis is divided into stages corresponding to the completion of one set of activities and the start of the next.
Indeed, it has been suggested that mechanical tension acts as an inhibitory signal for mitosis. [6] Moreover, it is important to note that such an inhibition of mitotic activity is a local phenomenon; it occurs between a select few cells in a likely heterogeneous culture.
Cell culture is a fundamental component of tissue culture and tissue engineering, as it establishes the basics of growing and maintaining cells in vitro. The major application of human cell culture is in stem cell industry, where mesenchymal stem cells can be cultured and cryopreserved for future use. Tissue engineering potentially offers ...
They may directly activate B cells through the PI3-kinase signalling pathway, regardless of their antigenic specificity. [11] Plasma cells are terminally differentiated and, therefore, cannot undergo mitosis. Memory B cells can proliferate to produce more memory cells or plasma B cells. This is how the mitogen works, that is, by inducing ...
The eukaryotic cell cycle consists of four distinct phases: G 1 phase, S phase (synthesis), G 2 phase (collectively known as interphase) and M phase (mitosis and cytokinesis). M phase is itself composed of two tightly coupled processes: mitosis, in which the cell's nucleus divides, and cytokinesis, in which the cell's cytoplasm and cell membrane divides forming two daughter cells.
Mitosis is the division of somatic cells into two daughter cells. Durations of the cell cycle and mitosis vary in different cell types. An elevated mitotic index indicates more cells are dividing. In cancer cells, the mitotic index may be elevated compared to normal growth of tissues or cellular repair of the site of an injury. [2]
Germ cells, or gametes, undergo meiosis, while somatic cells will undergo mitosis. After the cell proceeds successfully through the M phase, it may then undergo cell division through cytokinesis. The control of each checkpoint is controlled by cyclin and cyclin-dependent kinases. The progression of interphase is the result of the increased ...
Between the beginning of the G 1 phase (which is also after mitosis has occurred) and R, the cell is known as being in the G 1-pm subphase, or the post-mitotic phase. After R and before S, the cell is known as being in G 1-ps, or the pre S phase interval of the G 1 phase. [4]