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The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. [1] The epidermis layer provides a barrier to infection from environmental pathogens [2] and regulates the amount of water released from the body into the atmosphere through transepidermal water loss.
A failure to correctly regulate these processes leads to skin disorders developing. [4] Cells of the stratum corneum contain a dense network of keratin, a protein that helps keep the skin hydrated by preventing water evaporation. These cells can also absorb water, further aiding in hydration. In addition, this layer is responsible for the ...
Basal cells in the basal layer (stratum basale) of the skin are sometimes referred to as basal keratinocytes. [2] Keratinocytes form a barrier against environmental damage by heat , UV radiation , water loss , pathogenic bacteria , fungi , parasites , and viruses .
Skin's outermost layer, known colloquially as "the barrier," is responsible for keeping pathogens out and moisture in, and those suffering from inflammatory skin conditions already have a ...
It forms the outermost layer of the skin and the inner lining of the mouth, esophagus and vagina. [2] In the epidermis of skin in mammals, reptiles, and birds, the layer of keratin in the outer layer of the stratified squamous epithelial surface is named the stratum corneum. Stratum corneum is made up of squamous cells which are keratinized and ...
The epidermis, "epi" coming from the Greek language meaning "over" or "upon", is the outermost layer of the skin. It forms the waterproof, protective wrap over the body's surface, which also serves as a barrier to infection and is made up of stratified squamous epithelium with an underlying basal lamina.
As they are water-soluble themselves, excessive water contact may leach them and inhibit their normal functions which is why prolonged contact with water makes the skin drier. [14] The intercellular lipid layer helps prevent the loss of natural moisturizing factor by sealing the outside of each corneocyte.
Since the skin layer is in radiative equilibrium with the atmosphere and the sun, its temperature underlies a daily cycle. Even small changes in the skin temperature can lead to large changes in atmospheric circulation. This makes skin temperature a widely used quantity in weather forecasting and climate science.