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The elimination rate constant K or K e is a value used in pharmacokinetics to describe the rate at which a drug is removed from the human system. [1] It is often abbreviated K or K e. It is equivalent to the fraction of a substance that is removed per unit time measured at any particular instant and has units of T −1.
and this can be minimized with respect to the stability constant value, K, and a parameter such the chemical shift of the species HG (nmr data) or its molar absorbency (uv/vis data). The minimization can be performed in a spreadsheet application such as EXCEL by using the in-built SOLVER utility.
For example, the constant π may be defined as the ratio of the length of a circle's circumference to its diameter. The following list includes a decimal expansion and set containing each number, ordered by year of discovery. The column headings may be clicked to sort the table alphabetically, by decimal value, or by set.
The Van 't Hoff equation relates the change in the equilibrium constant, K eq, of a chemical reaction to the change in temperature, T, given the standard enthalpy change, Δ r H ⊖, for the process. The subscript r {\displaystyle r} means "reaction" and the superscript ⊖ {\displaystyle \ominus } means "standard".
The binding constant, or affinity constant/association constant, is a special case of the equilibrium constant K, [1] and is the inverse of the dissociation constant. [2] It is associated with the binding and unbinding reaction of receptor (R) and ligand (L) molecules, which is formalized as: R + L ⇌ RL
The ability to chain formulas together is what gives a spreadsheet its power. Many problems can be broken down into a series of individual mathematical steps, and these can be assigned to individual formulas in cells. Some of these formulas can apply to ranges as well, like the SUM function that adds up all the numbers within a range.
where log denotes a logarithm to base 10 or common logarithm, and K diss is a stepwise acid dissociation constant. For bases, the base association constant, pK b is used. For any given acid or base the two constants are related by pK a + pK b = pK w, so pK a can always be used in calculations.
The Boltzmann constant (k B or k) is the proportionality factor that relates the average relative thermal energy of particles in a gas with the thermodynamic temperature of the gas. [2] It occurs in the definitions of the kelvin (K) and the gas constant , in Planck's law of black-body radiation and Boltzmann's entropy formula , and is used in ...
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