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Sitagliptin, sold under the brand name Januvia among others, is an anti-diabetic medication used to treat type 2 diabetes. [8] In the United Kingdom it is listed as less preferred than metformin or a sulfonylurea. [9] It is taken by mouth. [8] It is also available in the fixed-dose combination medication sitagliptin/metformin (Janumet, Janumet ...
Clinical researches have shown that sitagliptin and vildagliptin do not have the side effects that tend to follow type 2 diabetes treatment, e.g. weight gain and hyperglycemia, but however, other side effects have been observed, including upper respiratory tract infections, sore throat and diarrhea. [5]
In 2013, Januvia was the second largest selling diabetes drug worldwide. [11] Januvia is commonly paired with the generic anti-diabetes drug metformin. It has been popular due in part because unlike many other diabetes drugs, it causes little or no weight gain and is not associated with hypoglycemic episodes.
For women, a drop in estrogen can cause weight gain, particularly in the abdomen (aka menopause belly). For men, low testosterone is linked to an increase in fat mass. Men with obesity are more ...
For the last several years, Merck has been able to ride the success of its leading type 2 diabetes franchise Januvia/Janumet, which generated $5.75 billion in sales last year and represented more ...
7. 63% of Americans Who Lose Weight Gain It Back the Same Year; 1 in 5 Gain it Back in 2 Months or Less. Among the 72% of Americans who have successfully lost weight in their lives, nearly two ...
Sitagliptin [6] (FDA approved 2006, marketed by Merck & Co. as Januvia) Vildagliptin [7] (EU approved 2007, marketed in the EU by Novartis as Galvus) Saxagliptin (FDA approved in 2009, marketed as Onglyza) Linagliptin (FDA approved in 2011, marketed as Tradjenta by Eli Lilly and Company and Boehringer Ingelheim) [8]
Diabetes drug Januvia has been a boon for Merck in recent years, and its massive year-over-year growth was one way the company was able to offset the huge losses incurred by Singulair's recent ...