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Phenylboronic acid or benzeneboronic acid, abbreviated as PhB(OH) 2 where Ph is the phenyl group C 6 H 5 - and B(OH) 2 is a boronic acid containing a phenyl substituent and two hydroxyl groups attached to boron. Phenylboronic acid is a white powder and is commonly used in organic synthesis.
4-Formylphenyl boronic acid crystallizes in colorless needles [2] or is obtained as an odorless, whitish powder, which dissolves little in cold but better in hot water. The compound is quite stable [4] and readily forms dimers and cyclic trimeric anhydrides, which complicate purification and tend to protodeboronize, a secondary reaction that occurs frequently in the Suzuki coupling, with ...
4-Nonylphenylboronic acid is a potent and selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH), with an IC 50 of 9.1nM, and 870x selectivity for FAAH over the related enzyme MAGL, which it inhibits with an IC 50 of 7900nM. [1]
N. 4-Nonylphenylboronic acid; P. Phenylboronic acid; Z. ZB716 This page was last edited on 27 March 2013, at 09:31 (UTC). Text is available under the Creative ...
The general structure of a boronic acid, where R is a substituent.. A boronic acid is an organic compound related to boric acid (B(OH) 3) in which one of the three hydroxyl groups (−OH) is replaced by an alkyl or aryl group (represented by R in the general formula R−B(OH) 2). [1]
They reported the reaction of phenylboronic acid in water (140-150 °C) to afford the protodeboronated product, benzene, after 40 hours. Initial synthetic applications of protodeboronation were found alongside the discovery of the hydroboration reaction, in which sequential hydroboration-protodeboronation reactions were used to convert alkynes ...
C 7 H 8 N 4 O 2: theophylline: 58-55-9 C 7 H 8 N 4 O 2: theobromine: C 7 H 9 BO 2: 4-methylphenylboronic acid: 5720-05-8 C 7 H 9 BO 3: 4-boronoanisole: 5720-07-0 C 7 H 10 N 2: 4-dimethylaminopyridine: 1122-58-3 C 7 H 11 NO 5: N-Acetylglutamic acid: C 7 H 12 O 4: diethyl malonate: C 7 H 12 N 2 O 4: aceglutamide: C 7 H 14 O 3: n-Butyl lactate ...
It also can be prepared by treating benzaldehyde under nitration conditions, a process that initially converts the aldehyde to the acid. 4-Nitrobenzoic acid is a precursor to 4-aminobenzoic acid, which is in turn used to prepare the anesthetic procaine. 4-Nitrobenzoic acid is prepared by oxidation of 4-nitrotoluene.