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Familial hypercholesterolemia (FH) is a genetic disorder characterized by high cholesterol levels, specifically very high levels of low-density lipoprotein cholesterol (LDL cholesterol), in the blood and early cardiovascular diseases.
High cholesterol is often silent, but this cardiologist looks for a common sign.
Hypercholesterolemia, also called high cholesterol, is the presence of high levels of cholesterol in the blood. [1] It is a form of hyperlipidemia (high levels of lipids in the blood), hyperlipoproteinemia (high levels of lipoproteins in the blood), and dyslipidemia (any abnormalities of lipid and lipoprotein levels in the blood). [1]
Cardiologist Dr. Stephanie Saucier, MD, FAAC, adds to this, saying, “There is an inherited genetic condition known as familial hypercholesterolemia where very high LDL cholesterol levels are ...
Hyperlipidemia is abnormally high levels of any or all lipids (e.g. fats, triglycerides, cholesterol, phospholipids) or lipoproteins in the blood. [2] The term hyperlipidemia refers to the laboratory finding itself and is also used as an umbrella term covering any of various acquired or genetic disorders that result in that finding. [3]
family history of high Lp(a), early-onset heart disease, familial hypercholesterolemia (FH) a personal history of heart attack, stroke, or coronary artery disease before 55 (for men) or before 65 ...
High cholesterol levels can cause arcus senilis, which presents as a gray-white ring around your eyes. ... This includes familial hypercholesterolemia (high cholesterol), familial ...
In familial hypercholesterolemia, a mutation in the LDLR, PCSK9, or APOB is usually the reason for this and these mutations result in high LDL cholesterol. [8] In combined hyperlipidemia, there is an overproduction of apoB-100 in the liver. [9] This causes high amounts of LDL and VLDL molecules to form. [9]