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In males, gonadarche is responsible for testicular enlargement and virilization. [4] In females, gonadarche is responsible for thelarche and menarche (first menstruation). [4] Gonadarche should be contrasted with adrenarche. Gonadarche indicates that true central puberty has begun, while adrenarche is an independent maturational process only ...
Adrenarche is an early stage in sexual maturation that happens in some higher primates (including humans), typically peaks at around 20 years of age, [1] [2] and is involved in the development of pubic hair, body odor, skin oiliness, axillary hair, sexual attraction/sexual desire/increased libido and mild acne.
It is usually the second sign of puberty, after thelarche in females and gonadarche in males (though in females, it can also happen before thelarche, but this is less common). The early stage of sexual maturation, also known as adrenarche , is marked by characteristics including the development of pubic hair, axillary hair , adult apocrine body ...
Adrenal maturation, termed adrenarche, typically precedes gonadarche in mid-childhood. Major hormones Neurokinin B (a tachykinin peptide ) and kisspeptin (a neuropeptide ), both present in KNDy neurons of the hypothalamus , are critical parts of the control system that switches on the release of GnRH at the start of puberty.
The activation of the HPG axis in both males and females during puberty also causes individuals to acquire secondary sex characteristics. This process, known as gonadarche, is preceded by adrenarche, the maturation of the adrenal glands, which contributes to the production of androgens responsible for some pubertal changes. [19]
Adrenarche; Gonadarche; Thelarche; Pubarche; Spermarche; Menopause, the equivalent opposite change at the end of the child-bearing years; Andropause; Delayed puberty; Lina Medina, who had her menarche at age 8 months and is the youngest mother in history
These changes are part of a process called adrenarche, which has only been described in humans and some other primates. Adrenarche is independent of ACTH or gonadotropins and correlates with a progressive thickening of the zona reticularis layer of the cortex. Functionally, adrenarche provides a source of androgens for the development of ...
The human Y chromosome showing the SRY gene which codes for a protein regulating sexual differentiation. Sexual differentiation in humans is the process of development of sex differences in humans.