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In human mitochondrial genetics, L is the mitochondrial DNA macro-haplogroup that is at the root of the anatomically modern human (Homo sapiens) mtDNA phylogenetic tree. As such, it represents the most ancestral mitochondrial lineage of all currently living modern humans, also dubbed "Mitochondrial Eve". Its two sub-clades are L1-6 and L0.
Haplogroup L4 is a human mitochondrial DNA (mtDNA) haplogroup. It is a small maternal clade primarily restricted to Africa. [2] Projected spatial frequency distribution for haplogroup L4. Schematic tree of mtDNA haplogroup L4. Ages (in ka) indicated are maximum likelihood estimates obtained for the whole-mtDNA genome. L4 is important in East ...
The hypothetical woman at the root of all these groups (meaning just the mitochondrial DNA haplogroups) is the matrilineal most recent common ancestor (MRCA) for all currently living humans. She is commonly called Mitochondrial Eve. The rate at which mitochondrial DNA mutates is known as the mitochondrial molecular clock. It is an area of ...
In 2014, ancient DNA analysis of a 2,330 year old male forager's skeleton in Southern Africa found that the specimen belonged to the L0d2c1c mtDNA subclade. This maternal haplogroup is today most closely associated with the Ju, a subgroup of the indigenous San people , which points to population continuity in the region. [ 4 ]
Projected spatial distribution of haplogroup L1 in Africa. Haplogroup L1 is a human mitochondrial DNA (mtDNA) haplogroup. It is most common in Central Africa and West Africa. It diverged from L1-6 at about 140,000 years ago (140.6 +33.7 −33.0 kya 95% CI). [3]
Haplogroup L2 is a human mitochondrial DNA (mtDNA) haplogroup with a widespread modern distribution, particularly in Subequatorial Africa. Its L2a subclade is a somewhat frequent and widely distributed mtDNA cluster on the continent, as well as among those in the Americas .
Mitochondrial DNA is the small circular chromosome found inside mitochondria. These organelles, found in all eukaryotic cells, are the powerhouse of the cell. [1] The mitochondria, and thus mitochondrial DNA, are passed exclusively from mother to offspring through the egg cell.
Haplogroup L3 is a human mitochondrial DNA (mtDNA) haplogroup.The clade has played a pivotal role in the early dispersal of anatomically modern humans.. It is strongly associated with the out-of-Africa migration of modern humans of about 70–50,000 years ago.