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Research has found that taking Viagra does not increase high blood pressure. Sildenafil, the active ingredient in Viagra, is actually used to treat a certain kind of high blood pressure in the lungs.
But the active ingredient began its clinical journey as a medication intended to treat hypertension (high blood pressure) and angina (chest pain due to high blood pressure). Sildenafil can still ...
Sildenafil (compound UK-92,480) was synthesized by a group of pharmaceutical chemists led by Simon Campbell [55] working at Pfizer's Sandwich, Kent, research facility in England. It was initially studied for use in hypertension (high blood pressure) and angina pectoris (a symptom of ischaemic heart disease). [56]
What Does Viagra Do? Viagra works by improving blood flow to your privates. The active ingredient, Sildenafil, is a PDE5 inhibitor that helps blood vessels relax. ... High blood pressure. Sickle ...
People with heart disease, high blood pressure, obesity, and other health conditions are at higher risk of ED and sometimes require a higher dose of medication. If you want a higher dose, seek ...
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
Sildenafil (marketed as Viagra) was the first PDE5 inhibitor on the market. Originally created as a treatment for high blood pressure in 1989, it was found to have a secondary use as an effective PDE5 inhibitor, enabling men who use it to gain stronger erections after arousal. The FDA approved Viagra on March 27, 1998. [20]
Sildenafil and other PDE-5 inhibitor medications can interact with other drugs, including several common medications used to treat chest pain, high blood pressure (sildenafil can cause low blood ...
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