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Methylecgonine cinnamate is a natural tropane alkaloid found within the coca plant. [1] Its more common name, cinnamoylcocaine , reflects its close structural similarity to cocaine . It is pharmacologically inactive, [ 2 ] but some studies funded by anti-drug agencies imply that it is active when smoked.
Methylecgonine, also known as ecgonine methyl ester is a prominent tropane alkaloid found in coca leaves. [1] It is metabolite of cocaine, [2] and may be used as a precursor for it. It also occurs as minor alkaloid in roots of many Datura species such as Datura stramonium [3] and Datura innoxia. [4]
Ecgonine (tropane derivative) is a tropane alkaloid found naturally in coca leaves. It has a close structural relation to cocaine: it is both a metabolite and a precursor, and as such, it is a controlled substance in many jurisdictions, as are some substances which can be used as precursors to ecgonine itself.
Chemical structure of tropane which forms the core of tropane alkaloids Chemical structure and phylogeny of tropane alkaloids. Displayed are 3 chemical compounds that occur as natural products in 5 plant species. Tropane alkaloids are a class of bicyclic [3.2.1] alkaloids and secondary metabolites that contain a tropane ring in their chemical ...
Of the approximately 200 members in the genus Erythroxylum, most species contain the central nervous system stimulant tropane alkaloid, known more commonly as cocaine.Because the plant is endemic ...
the average cocaine alkaloid content of a sample of coca leaf varied between 0.1 and 0.8 percent, with coca from higher altitudes containing the largest percentages of cocaine alkaloids; the typical farmer will plant coca on a sloping hill so rainfall will not drown the plants as they reach full maturity over 12 to 24 months after being planted
Tropinone is an alkaloid, famously synthesised in 1917 by Robert Robinson as a synthetic precursor to atropine, a scarce commodity during World War I. [2] [3] Tropinone and the alkaloids cocaine and atropine all share the same tropane core structure. Its corresponding conjugate acid at pH 7.3 major species is known as tropiniumone. [4]
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