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[1] [4] Chloroquine is a member of the drug class 4-aminoquinoline. [1] As an antimalarial, it works against the asexual form of the malaria parasite in the stage of its life cycle within the red blood cell. [1] How it works in rheumatoid arthritis and lupus erythematosus is unclear. [1] Chloroquine was discovered in 1934 by Hans Andersag.
The drug should be given in doses between 25 mg/kg and 35 mg/kg over three days in a similar method to that used in chloroquine administration. Adverse reactions are generally similar in severity and type to that seen in chloroquine treatment. [11] In addition, bradycardia, itching, nausea, vomiting and some abdominal pain have been recorded.
Chloroquine and hydroxychloroquine are anti-malarial medications also used against some auto-immune diseases. [51] Chloroquine, along with hydroxychloroquine, was an early experimental treatment for COVID-19. [52] Neither drug has been useful to prevent or treat SARS-CoV-2 infection.
Chloroquine and hydroxychloroquine are anti-malarial medications also used against some auto-immune diseases. [1] Chloroquine, along with hydroxychloroquine, was an early experimental treatment for COVID-19. [2] Neither drug has been useful to prevent or treat SARS-CoV-2 infection.
American troops, on capturing Tunisia during the Second World War, acquired, then altered the drugs to produce chloroquine. The development of new antimalarial drugs spurred the World Health Organization in 1955 to attempt a global malaria eradication program. This was successful in much of Brazil, the US and Egypt but ultimately failed elsewhere.
A common antibiotic used to treat liver disease could give rise to an “almost untreatable” superbug, scientists warned in a new study.. The antibiotic, rifaximin, has enabled the global ...
Metformin is available to treat type 2 diabetes as-is, and is also used with other drugs in some medications to treat diabetes, according to the U.S. National Library of Medicine.
Antibiotics with less reliable but occasional (depending on isolate and subspecies) activity: occasionally penicillins including penicillin, ampicillin and ampicillin-sulbactam, amoxicillin and amoxicillin-clavulnate, and piperacillin-tazobactam (not all vancomycin-resistant Enterococcus isolates are resistant to penicillin and ampicillin)