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Smokers and the elderly are also at an increased risk. Outside of this context, atelectasis implies some blockage of a bronchiole or bronchus, which can be within the airway (foreign body, mucus plug), from the wall (tumor, usually squamous cell carcinoma) or compressing from the outside (tumor, lymph node, tubercle).
Lung cancer, also known as lung carcinoma, is a malignant tumor that begins in the lung. Lung cancer is caused by genetic damage to the DNA of cells in the airways, often caused by cigarette smoking or inhaling damaging chemicals. Damaged airway cells gain the ability to multiply unchecked, causing the growth of a tumor.
In the United States there has been an increase in the 5-year relative survival rate between people diagnosed with cancer in 1975-1977 (48.9%) and people diagnosed with cancer in 2007-2013 (69.2%); these figures coincide with a 20% decrease in cancer mortality from 1950 to 2014. [8]
Squamous-cell carcinoma of the lung is closely correlated with a history of tobacco smoking, more so than most other types of lung cancer.According to the Nurses' Health Study, the relative risk of SCC is approximately 5.5, both among those with a previous duration of smoking of 1 to 20 years, and those with 20 to 30 years, compared to never-smokers. [2]
The lower respiratory tract is also called the respiratory tree or tracheobronchial tree, to describe the branching structure of airways supplying air to the lungs, and includes the trachea, bronchi and bronchioles. [8] trachea. main bronchus (diameter approximately 1 – 1.4 cm in adults) [9] lobar bronchus (diameter approximately 1 cm)
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Photograph of a squamous-cell carcinoma. The tumour is on the left, obstructing the bronchus (lung); beyond the tumour, the bronchus is inflamed and contains mucus. When associated with the lung, it is typically a centrally located large-cell cancer (non-small-cell lung cancer).
Researchers at the Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine say that individuals experiencing accelerated aging may benefit from earlier screenings.