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Hydrocodone/ibuprofen , sold under the brand name Vicoprofen, is a fixed-dose combination analgesic medication used in short-term therapy to relieve severe pain. [ 3 ] [ 4 ] Vicoprofen combines the analgesic and antitussive properties of hydrocodone with the analgesic, anti-inflammatory, and antipyretic properties of ibuprofen . [ 1 ]
Additive effect often occurs when two similar drugs are taken together to achieve the same degree of therapeutic effect while reducing the specific adverse effect of one particular drug. For example, aspirin, paracetamol, and caffeine are formulated together to treat pain caused by tension headaches and migraine .
Ibuprofen/paracetamol, sold under the brand name Combogesic among others, is a fixed-dose combination of two medications, ibuprofen, a non-steroidal anti-inflammatory drug (NSAID); and paracetamol (acetaminophen), an analgesic and antipyretic. [6] It is available as a generic medication. [9] [10] [11]
Take over-the-counter (OTC) medications and home remedies to manage a fever and pain with acetaminophen (Tylenol) and ibuprofen (Advil). Note: Talk to your provider before taking any cold medications.
Paracetamol, [a] or acetaminophen, [b] is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. [13] [14] [15] It is a widely available over-the-counter drug sold under various brand names, including Tylenol and Panadol. Paracetamol relieves pain in both acute mild migraine and episodic tension headache.
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Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, fever, and inflammation. [8] This includes painful menstrual periods, migraines, and rheumatoid arthritis. [8] It may also be used to close a patent ductus arteriosus in a premature baby. [9] [8] It can be taken orally (by mouth) or intravenously. [8]
The effectiveness of acetaminophen alone as an antipyretic in children is uncertain, with some evidence showing it is no better than physical methods. [14] Therapies involving alternating doses of acetaminophen and ibuprofen have shown greater antipyretic effect than either drug alone. [15]