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  2. List of drugs by year of discovery - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_by_year_of...

    The following is a table of drugs organized by their year of discovery. Naturally occurring chemicals in plants, including alkaloids, have been used since pre-history. In the modern era, plant-based drugs have been isolated, purified and synthesised anew.

  3. Diazepam - Wikipedia

    en.wikipedia.org/wiki/Diazepam

    Diazepam can substitute for the behavioral effects of barbiturates in a primate study. [129] Diazepam has been found as an adulterant in heroin. [130] Diazepam drug misuse can occur either through recreational misuse where the drug is taken to achieve a high or when the drug is continued long term against medical advice. [131]

  4. List of benzodiazepines - Wikipedia

    en.wikipedia.org/wiki/List_of_benzodiazepines

    The tables below contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses.

  5. Benzodiazepine - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine

    Like diazepam it has a long elimination half-life and long-acting active metabolites. Discontinuation of benzodiazepines or abrupt reduction of the dose, even after a relatively short course of treatment (two to four weeks), may result in two groups of symptoms, rebound and withdrawal. Rebound symptoms are the return of the symptoms for which ...

  6. Timeline of scientific discoveries - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_scientific...

    The timeline begins at the Bronze Age, as it is difficult to give even estimates for the timing of events prior to this, such as of the discovery of counting, natural numbers and arithmetic. To avoid overlap with timeline of historic inventions , the timeline does not list examples of documentation for manufactured substances and devices unless ...

  7. Leo Sternbach - Wikipedia

    en.wikipedia.org/wiki/Leo_Sternbach

    Librium, based on the R0 6-690 compound discovered by Sternbach in 1956, was approved for use in 1960. In 1963, its improved version, Valium, was released and became astonishingly popular: between 1969 and 1982, it was the most prescribed drug in America, with over 2.3 billion doses sold in its peak year of 1978.

  8. History and culture of substituted amphetamines - Wikipedia

    en.wikipedia.org/wiki/History_and_culture_of...

    In 1997 and 1998, researchers at Texas A&M University claimed to have found amphetamine and methamphetamine in the foliage of two Acacia species native to Texas, A. berlandieri and A. rigidula. [31] [32] Previously, both of these compounds had been thought to be purely synthetic.

  9. History of Texas - Wikipedia

    en.wikipedia.org/wiki/History_of_Texas

    The first European to see Texas was Alonso Álvarez de Pineda, who led an expedition for the governor of Jamaica, Francisco de Garay, in 1520.While searching for a passage between the Gulf of Mexico and Asia, [17] Álvarez de Pineda created the first map of the northern Gulf Coast. [18]