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Dorzolamide, sold under the brand name Trusopt among others, is a medication used to treat high pressure inside the eye, including in cases of glaucoma. [3] It is used as an eye drop. [ 3 ] Effects begin within three hours and last for at least eight hours. [ 3 ]
Dorzolamide/timolol, sold under the brand name Cosopt among others, is a medication used to treat high pressure inside the eye including glaucoma. [3] [5] [6] It is a combination of dorzolamide hydrochloride and timolol maleate. [3] It may be used when a beta blocker, like timolol, is not sufficient alone. [7] It is used as an eye drop. [3]
Dorzolamide: Trusopt: Decrease aqueous production: Every 8–12 hours: 15-20%: eye irritation, bitter taste Brinzolamide: Azopt: Decrease aqueous production: Every 8–12 hours: 15-20%: eye irritation, bitter taste Acetazolamide: Diamox: Decrease aqueous production: Every 6–12 hours: 15-20%: malaise, depression, weight loss, kidney stones
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Dorzolamide is a sulfonamide and topical carbonic anhydrase II inhibitor. It is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension and who are insufficiently responsive to beta-blockers. Inhibition of carbonic anhydrase II in the ciliary processes of the eye decreases aqueous ...
Here are links to possibly useful sources of information about Dorzolamide. PubMed provides review articles from the past five years (limit to free review articles ) The TRIP database provides clinical publications about evidence-based medicine .
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