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2. Spironolactone - Wikipedia

   en.wikipedia.org/wiki/Spironolactone

   Because of its antiandrogenic activity, spironolactone can cause breast tenderness, gynecomastia (breast development), feminization in general, and demasculinization, as well as sexual dysfunction including loss of libido and erectile dysfunction, although these side effects are usually confined to high doses of spironolactone. [109]

3. Does Low Estrogen Cause Hair Loss? - AOL

   www.aol.com/does-low-estrogen-cause-hair...

   These topical formulations may have fewer side effects than other treatments like spironolactone. ... From minoxidil to spironolactone, various effective hair loss treatments can help kick-start ...

4. Mineralocorticoid receptor antagonist - Wikipedia

   en.wikipedia.org/wiki/Mineralocorticoid_receptor...

   However, spironolactone is metabolized to three active metabolites, which give it prolonged activity (13.8 – 16. 5 hours). Spironolactone has a long half-life and is excreted 47-51% through kidneys. Patients with chronic kidney disease therefore require close monitoring when taking the drug. Spironolactone is also eliminated through feces (35-41%

5. 8 Medications That Cause Hair Loss ( & What to Do About It) - AOL

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   Hair loss is a well-known side effect of many chemotherapy drugs used to treat certain forms of cancer. Similar to other toxins that cause hair loss, hair loss from cancer medications usually isn ...

6. Template : Side effects of spironolactone in women in ...

   en.wikipedia.org/wiki/Template:Side_effects_of...

   Description: Side effects of spironolactone (25–400 mg/day) with ≥1% incidence in a 2017 hybrid systematic review of clinical studies of spironolactone for acne in women. Side effects with <1% incidence included postural hypotension, depression, diarrhea, muscle pain, increased appetite, drowsiness, rashes/drug eruptions, chloasma-like skin ...

7. Hair Loss in Women: Everything You Need to Know - AOL

   www.aol.com/hair-loss-women-everything-know...

   Spironolactone is a once-a-day tablet that can stop hair loss from progressing and encourage new hair growth. It’s especially useful for women with hormonal issues like PCOS. It may take six to ...

8. Could Spironolactone Help Women With Hair Thinning, Facial ...

   www.aol.com/lifestyle/could-spironolactone-help...

   This can be overwhelming, from looking up hair loss treatments to scouring social media. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290-4726 ...

9. Pharmacodynamics of spironolactone - Wikipedia

   en.wikipedia.org/wiki/Pharmacodynamics_of...

   Spironolactone has been identified as an inhibitor of NRG1‐ERBB4 signaling. [142] Spironolactone has been found to act as a potent inhibitor of the pannexin 1 channel, and this action appears to be involved in its antihypertensive effects independently of MR antagonism. [143] Spironolactone has been found to block hERG channels. [144]