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Ketamine, popularly known as the party drug Special K, has recently been hailed as a breakthrough treatment for major depression. But it is not without risks. But it is not without risks. What is ...
Noting that the lack of information about adverse effects of using the drug is "disappointing," Dr. Sanacora added that ketamine use comes with a "unique set of risks, both to the individual but ...
Ketamine is generally safe when taken under medical supervision, experts said, but the Perry case also underscores potential risks. Ketamine is generally safe when taken under medical supervision ...
Dissociation and psychotomimetic effects are reported in people treated with ketamine at plasma concentrations of approximately 100 to 250 ng/mL (0.42–1.1 μM). [20] The typical intravenous antidepressant dosage of ketamine used to treat depression is low and results in maximal plasma concentrations of 70 to 200 ng/mL (0.29–0.84 μM). [58]
In Brazil, pharmacological torture involved the injection of alcohol into the tongue in the 1940s, the injection of ether into the scrotum in the 1960s, and drugs were used to cause strong contractions in the 1970s. Also, muscle relaxants were used to minimize muscular rigidity and bone fractures caused by electric shock in the 1970s. [4] [2]
NMDA receptor antagonists induce a state called dissociative anesthesia, marked by catalepsy, amnesia, and analgesia. [1] Ketamine is a favored anesthetic for emergency patients with unknown medical history and in the treatment of burn victims because it depresses breathing and circulation less than other anesthetics.
Matthew Perry died in his Pacific Palisades home on Oct. 28, 2023, from the “acute effects of ketamine.” Now, five people have been arrested in connection with his death. This includes two ...
Ketamine crystals on a glass plate. K-hole is the feeling of getting a high enough dose of ketamine to experience a state of dissociation.This intense detachment from reality is often a consequence of accidental overconsumption of ketamine; however, some users consciously seek out the k-hole as they find the powerful dissociative effects to be quite pleasurable and enlightening.
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