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The choice of urinary anti-infective agents for patients with renal dysfunction is generally similar to that for individuals with normal kidney function. However, in cases where the patient's glomerular filtration rate (GFR) decreases to less than 20 mL/min, drug dosages adjustment is necessary because achieving the desired therapeutic serum ...
Amikacin should be used in smaller doses in the elderly, who often have age-related decreases in kidney function, and children, whose kidneys are not fully developed yet. It is considered pregnancy category D in both the United States and Australia, meaning they have a probability of harming the fetus. [ 9 ]
If taken intravenously, the half-life is generally 2.0–2.5 hours in a patient with normal kidney function and normal creatinine clearance. [medical citation needed] In patients with kidney dysfunction, the half-life may increase to 4 to 5 hours. [125] Excretion: The primary route of excretion is the urine. [125]
Ciclosporin — patients who have received a kidney transplant and are receiving co-trimoxazole and ciclosporin concomitantly are at an increased risk of having a reversible deterioration in their kidney function. Spironolactone — concurrent use can increase the likelihood of hyperkalemia, especially in the elderly. The trimethoprim portion ...
When given for short periods, linezolid is a relatively safe antibiotic. [12] It can be used in people of all ages and in people with liver disease or poor kidney function. [10] Common side effects with short-term use include headache, diarrhea, rash, and nausea. [10]
Other common manifestations include kidney stones and loss of function of the affected kidney. Bacterial cultures of kidney tissue are almost always positive. [25] Microscopically, there are granulomas and lipid-laden macrophages (hence the term xantho-, which means yellow in ancient Greek). It is found in roughly 20% of specimens from ...
Furosemide should be used with caution when combined with corticosteroids (as this increases the risk of electrolyte imbalance), aminoglycoside antibiotics (increases the risk of kidney or ear damage), and trimethoprim sulfa (causes decreased platelet count).
Norfloxacin, sold under the brand name Noroxin among others, is an antibiotic [1] [2] that belongs to the class of fluoroquinolone antibiotics.It is used to treat urinary tract infections, gynecological infections, inflammation of the prostate gland, gonorrhea and bladder infection.
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