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  2. Reproducibility Project - Wikipedia

    en.wikipedia.org/wiki/Reproducibility_Project

    [3] [4] The results of the Reproducibility Project might also affect public trust in psychology. [9] [10] Lay people who learned about the low replication rate found in the Reproducibility Project subsequently reported a lower trust in psychology, compared to people who were told that a high number of the studies had replicated. [11] [9]

  3. Hayflick limit - Wikipedia

    en.wikipedia.org/wiki/Hayflick_limit

    Hayflick describes three phases in the life of normal cultured cells. At the start of his experiment he named the primary culture "phase one". Phase two is defined as the period when cells are proliferating; Hayflick called this the time of "luxuriant growth".

  4. Replication - Wikipedia

    en.wikipedia.org/wiki/Replication

    Replication (scientific method), one of the main principles of the scientific method, a.k.a. reproducibility Replication (statistics), the repetition of a test or complete experiment; Replication crisis; Self-replication, the process in which an entity (a cell, virus, program, etc.) makes a copy of itself

  5. Eukaryotic DNA replication - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_DNA_replication

    This is known as the end replication problem. [1] The end replication problem is handled in eukaryotic cells by telomere regions and telomerase. Telomeres extend the 3' end of the parental chromosome beyond the 5' end of the daughter strand. This single-stranded DNA structure can act as an origin of replication that recruits telomerase.

  6. DNA replication - Wikipedia

    en.wikipedia.org/wiki/DNA_replication

    In molecular biology, [1] [2] [3] DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule. [4] DNA replication occurs in all living organisms acting as the most essential part of biological inheritance .

  7. DNA re-replication - Wikipedia

    en.wikipedia.org/wiki/DNA_re-replication

    DNA re-replication (or simply rereplication) is an undesirable and possibly fatal occurrence in eukaryotic cells in which the genome is replicated more than once per cell cycle. [1] Rereplication is believed to lead to genomic instability and has been implicated in the pathologies of a variety of human cancers . [ 2 ]

  8. Cell cycle checkpoint - Wikipedia

    en.wikipedia.org/wiki/Cell_cycle_checkpoint

    In eukaryotes, the cell cycle consists of four main stages: G 1, during which a cell is metabolically active and continuously grows; S phase, during which DNA replication takes place; G 2, during which cell growth continues and the cell synthesizes various proteins in preparation for division; and the M phase, during which the duplicated ...

  9. Self-replication - Wikipedia

    en.wikipedia.org/wiki/Self-replication

    Self-replication is a fundamental feature of life. It was proposed that self-replication emerged in the evolution of life when a molecule similar to a double-stranded polynucleotide (possibly like RNA) dissociated into single-stranded polynucleotides and each of these acted as a template for synthesis of a complementary strand producing two double stranded copies. [4]