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The causes of nerve damage are grouped into categories including those due to paraneoplastic causes (neuropathy secondary to cancer), immune mediated, infectious, inherited or degenerative causes and those due to toxin exposure. In idiopathic sensory neuronopathy no cause is identified. Idiopathic causes account for about 50% of cases. [2]
This is a list of major and frequently observed neurological disorders (e.g., Alzheimer's disease), symptoms (e.g., back pain), signs (e.g., aphasia) and syndromes (e.g., Aicardi syndrome). There is disagreement over the definitions and criteria used to delineate various disorders and whether some of these conditions should be classified as ...
Familial hemiplegic migraine (FHM) is migraine with a possible polygenetic cause—in fact, FHM can only be diagnosed when at least one close relative has it too. [7] The patient experiences typical migraine with aura headache either preceded or accompanied with one-sided, reversible limb weakness and/or sensory difficulties and/or speech ...
Neuropathy disorders usually have onset in childhood or young adulthood. Motor symptoms seem to be more predominant than sensory symptoms. [2] Symptoms of these disorders include: fatigue, pain, lack of balance, lack of feeling, lack of reflexes, and lack of sight and hearing, which result from muscle atrophy.
Sensory overload has been found to be associated with other disorders and conditions such as: Attention deficit hyperactivity disorder (ADHD) People with ADHD display hypersensitivity to sensory stimuli from a young age; this hypersensitivity often persists into adulthood.
Autonomic disturbances, if present, manifest as decreased sweating. [3] [8] The degree of motor disturbances is highly variable, even within families, ranging from absent to severe distal muscle weakness and wasting. [1] The disease progresses slowly, but often disables the affected individuals severely after a long duration.
This disorder is characterized by the adult-onset triad consisting of the following symptoms: sensory ataxic neuropathy, dysarthria, and ophthalmoparesis. MRIS often reveals white matter abnormalities and bilateral thalamus lesions. Other symptoms include generalized myopathy, epilepsy, and deafness. [1] [2]
Blood tests are performed to rule out other causes and to confirm an elevated level of vitamin B 6 with an absence of hypophosphatasia. [ 14 ] [ 11 ] [ 12 ] [ 56 ] [ 57 ] Examination does not typically show signs of a motor deficit , dysfunction of the autonomic nervous system or impairment of the central nervous system , [ 4 ] [ 3 ] although ...