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A Cochrane review found limited evidence for its possible antipsychotic effects in the treatment of schizophrenia and called for more studies. [164] Another review found limited evidence for its use as an add-on therapy for the relief of symptoms but positive results were found for the treatment of sleep disorders that often accompany ...
Diagnosis of schizophrenia from non-psychotic disorders Sensitivity 61.8 (51.7, 71.0) Specificity 94.1 (88.0, 97.2) 55% (19% to 89%) With a prevalence of 55%, 55 out of every 100 people with non-psychotic disorders will have schizophrenia. Of these, 21 will not be identified as having schizophrenia by use of FRS (38% of 55).
Clozapine is an example of a drug used in the treatment of certain CNS disorders, such as schizophrenia, that has superior efficacy precisely because of its broad-spectrum mode of action. Likewise, in cancer chemotherapeutics, it has been recognized that drugs active at more than one target have a higher probability of being efficacious.
In patients under the age of 65, 71% of patients were prescribed an atypical antipsychotic to treat Schizophrenia or Bipolar Disorder where this dropped to 38% in patients aged 65 or above. [46] Despite the name "antipsychotics", the drugs are commonly used for a variety of conditions that do not involve psychosis. Some healthcare professionals ...
The conversion rate for a first episode of drug induced psychosis to bipolar disorder or schizophrenia is lower, with 30% of people converting to either bipolar disorder or schizophrenia. [34] NICE makes no distinction between substance-induced psychosis and any other form of psychosis. The rate of conversion differs for different classes of ...
When comorbid with schizophrenia, substance use disorder and antisocial personality disorder both increase the risk for violence. [169] Comorbid substance use disorder also increases the risk of suicide. [120] Sleep disorders often co-occur with schizophrenia, and may be an early sign of relapse. [170]
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