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Bromocriptine is a partial agonist of the dopamine D 2 receptor. [ 21 ] [ 22 ] [ 23 ] It also interacts with other dopamine receptors and with various serotonin and adrenergic receptors . [ 21 ] [ 22 ] [ 24 ] Bromocriptine has additionally been found to inhibit the release of glutamate by reversing the GLT1 glutamate transporter .
Prolactin inhibitors are mainly used to treat hyperprolactinemia (high prolactin levels). [1] Agonists of the dopamine D 2 receptor such as bromocriptine and cabergoline are able to strongly suppress pituitary prolactin secretion and thereby decrease circulating prolactin levels, and so are most commonly used as prolactin inhibitors. [1]
[citation needed] Although cabergoline is commonly described principally as a D 2 receptor agonist, it also possesses significant affinity for the dopamine D 3, and D 4, serotonin 5-HT 1A, 5-HT 2A, 5-HT 2B, and 5-HT 2C, and α 2-adrenergic receptors, as well as moderate/low affinity for the dopamine D 1, serotonin 5-HT 7, and α 1-adrenergic ...
PSA levels between 4 and 10 suggest you could have about a 25 percent chance of prostate cancer, and levels over 10 signal that your chance of having the cancer is more than 50 percent.
In fact, a study in The Journal of Sexual Medicine found that nipple stimulation is arousing for 52% of men—yet only 17% of men have had their nipples played with during sex. Clearly, there’s ...
Additionally, many medications – both prescribed and over-the-counter - have common side effects, such as lightheadedness or confusion, that can lead to falls, so it is important for people to ...
If spiperone was added as soon as 1 min after I, the antagonist was unable to block the complete expression of the I inhibition. Evidently, I is a functionally irreversible dopamine agonist for at least the 4 h of these studies." source: European Journal of Pharmacology 1984, 99(1), p.85 Nagelfar 19:03, 20 October 2008 (UTC)
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