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Section of a thyroid gland under the microscope. 1 colloid, 2 follicular cells, 3 endothelial cells. At the microscopic level, there are three primary features of the thyroid—thyroid follicles, thyroid follicular cells, and parafollicular cells, first discovered by Geoffery Websterson in 1664. [14] Follicles
Thyroid follicular cells (also called thyroid epithelial cells or thyrocytes [1]) are the major cell type in the thyroid gland, and are responsible for the production and secretion of the thyroid hormones thyroxine (T 4) and triiodothyronine (T 3).
Parafollicular cells, also called C cells, are neuroendocrine cells in the thyroid. They are called C cells because the primary function of these cells is to secrete calcitonin. [1] They are located adjacent to the thyroid follicles and reside in the connective tissue. These cells are large and have a pale stain compared with the follicular cells.
Simple cuboidal epithelium is a type of epithelium that consists of a single layer of cuboidal (cube-like) cells which have large, spherical and central nuclei.. Simple cuboidal epithelium is found on the surface of ovaries, the lining of nephrons, the walls of the renal tubules, parts of the eye and thyroid, and in salivary glands.
Anaplastic thyroid cancer (ATC), also known as anaplastic thyroid carcinoma, is an aggressive form of thyroid cancer characterized by uncontrolled growth of cells in the thyroid gland. This form of cancer generally carries a very poor prognosis due to its aggressive behavior and resistance to cancer treatments. [ 1 ]
As the developing thyroid begins to travel to its intended destination, it remains connected to the tongue via the thyroglossal duct. By the seventh week of fetal development, the thyroid reaches its final position in the neck after growing through the mesoderm and musculature of the tongue, mouth, and neck. During the eighth to tenth week, the ...
The two lobes differ slightly in size, with the left lobe usually higher than the right. Thymic tissue may be found scattered on or around the gland, and occasionally within the thyroid. [2] The thymus in children stretches variably upwards, at times to as high as the thyroid gland. [2]
The thyroid gland also stretches across the upper trachea, with the isthmus overlying the second to fourth rings, and the lobes stretching to the level of the fifth or sixth cartilage. [2] The blood vessels of the thyroid rest on the trachea next to the isthmus; superior thyroid arteries join just above it, and the inferior thyroid veins below ...
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