enow.com Web Search

Search results

  1. Results from the WOW.Com Content Network
  2. Dopamine receptor D1 - Wikipedia

    en.wikipedia.org/wiki/Dopamine_receptor_D1

    D 1 receptor has a high degree of structural homology to another dopamine receptor, D 5, and they both bind similar drugs. [13] As a result, none of the known orthosteric ligands is selective for the D 1 vs. the D 5 receptor, but the benzazepines generally are more selective for the D 1 and D 5 receptors versus the D 2 -like family. [ 12 ]

  3. Dopamine receptor - Wikipedia

    en.wikipedia.org/wiki/Dopamine_receptor

    Dopamine receptors can also transactivate Receptor tyrosine kinases. [19] Beta Arrestin recruitment is mediated by G-protein kinases that phosphorylate and inactivate dopamine receptors after stimulation. While beta arrestin plays a role in receptor desensitization, it may also be critical in mediating downstream effects of dopamine receptors.

  4. Dopamine agonist - Wikipedia

    en.wikipedia.org/wiki/Dopamine_agonist

    There are two fundamental ways of treating Parkinson's disease, either by replacing dopamine or mimicking its effect. [1] Dopamine agonists act directly on the dopamine receptors and mimic dopamine's effect. [1] Dopamine agonists have two subclasses: ergoline and non-ergoline agonists. Both subclasses target dopamine D 2-type receptors.

  5. A-68930 - Wikipedia

    en.wikipedia.org/wiki/A-68930

    A-68930 is a synthetic compound that acts as a selective dopamine receptor D 1 agonist. [1] [2] It is orally active and has antidepressant and anorectic effects in ...

  6. Dopamine antagonist - Wikipedia

    en.wikipedia.org/wiki/Dopamine_antagonist

    A dopamine antagonist, also known as an anti-dopaminergic and a dopamine receptor antagonist (DRA), is a type of drug which blocks dopamine receptors by receptor antagonism. Most antipsychotics are dopamine antagonists, and as such they have found use in treating schizophrenia , bipolar disorder , and stimulant psychosis . [ 1 ]

  7. Motivation-enhancing drug - Wikipedia

    en.wikipedia.org/wiki/Motivation-enhancing_drug

    [134] [135] On the other hand, another study found that aripiprazole reversed stress-induced motivational anhedonia in animals, an antidepressant-like effect. [136] [137] Different dopamine receptor partial agonists that are used in the treatment of schizophrenia are known to vary in their intrinsic activities at the dopamine receptors, so each ...

  8. D1-like receptor - Wikipedia

    en.wikipedia.org/wiki/D1-like_receptor

    The D 1-like receptors are a subfamily of dopamine receptors that bind the endogenous neurotransmitter dopamine. [1] The D 1 -like subfamily consists of two G protein–coupled receptors that are coupled to G s and mediate excitatory neurotransmission , of which include D 1 and D 5 . [ 2 ]

  9. Medium spiny neuron - Wikipedia

    en.wikipedia.org/wiki/Medium_spiny_neuron

    Medium spiny neurons have two primary phenotypes (characteristic types): D1-type MSNs of the direct pathway and D2-type MSNs of the indirect pathway. [2] [3] [4] Most striatal MSNs contain only D1-type or D2-type dopamine receptors, but a subpopulation of MSNs exhibit both phenotypes. [2] [3] [4]