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Bag and contents of a well-known early brand of synthetic cannabinoids named k2 spice that contains herbs covered with synthetic cannabinoids, now illegal throughout much of the world. Synthetic cannabinoids are a class of designer drug molecules that bind to the same receptors to which cannabinoids (THC, CBD and many others) in cannabis plants ...
Cannabinoids and their K i values [a]; Name Class K i / nM at CB 1 K i / nM at CB 2 Selectivity Structure JWH-004: Naphthoylindole: 48 ± 13: 4 ± 1.5: CB 2 (12x): JWH-007 [5]: Naphthoylindole: 9.5 ± 4.5
JWH-018 is a full agonist of both the CB 1 and CB 2 cannabinoid receptors, with a reported binding affinity of 9.00 ± 5.00 nM at CB 1 and 2.94 ± 2.65 nM at CB 2. [6] JWH-018 has an EC 50 of 102 nM for human CB 1 receptors, and 133 nM for human CB 2 receptors. [16]
Marketed under the names spice, spike, flamingo, or K2 — this underground drug has become one of the most inexpensive and dangerous ways to get high, reports say. Videos surfacing online have ...
It bothers me that people are so stupid as to use this stuff". [6] Huffman may have developed these compounds for scientific research, but as of 2011 he was blamed for its abuse. [7] As JWH-018 is more potent and easy to make, Huffman believes it is a more widely used synthetic cannabinoid of the JWH series. [8]
JWH-018, a potent synthetic cannabinoid agonist discovered by John W. Huffman at Clemson University. It was often sold in legal smoke blends collectively known as "spice". Several countries and states have moved to ban it legally. JWH-073; CP-55940, produced in 1974, this synthetic cannabinoid receptor agonist is many times more potent than THC.
When the clock strikes midnight on Dec. 1, the site flips to Wayfair's Cyber Monday event, so don't dillydally if there's something from the Black Friday sale that catches your eye. Best Wayfair ...
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