Search results
Results from the WOW.Com Content Network
The researchers failed to notify and withheld treatment for patients despite knowing penicillin was found as an effective cure for syphilis. After four years of follow-up, neurosyphilis was identified in 26.1% of patients vs. 2.5% of controls. [23] After 20 years of follow-up, 6.5% showed signs of neurosyphilis and 40% had died from other ...
Meningeal syphilis (as known as syphilitic aseptic meningitis or meningeal neurosyphilis) is a chronic form of syphilis infection that affects the central nervous system. Treponema pallidum , a spirochate bacterium, is the main cause of syphilis, which spreads drastically throughout the body and can infect all its systems if not treated ...
Pleocytosis, raised CSF protein level and positive CSF serology suggest neurosyphilis. [31] CSF VDRL is 50-90% specific for neurosyphilis. [18] 60% of newborns with congenital syphilis also have neurosyphilis. [18] Non-treponemal titers should be monitored in the newborns every 2-3 months to ensure an adequate response to treatment. [18]
In those with neurosyphilis, intravenous benzylpenicillin or ceftriaxone is recommended. [4] During treatment, people may develop fever, headache, and muscle pains, a reaction known as Jarisch–Herxheimer. [4] In 2015, about 45.4 million people had syphilis infections, [5] of which six million were new cases. [9]
These potential morbidities include Hutchinson’s triad, thickening of the clavicle, juvenile paresis, juvenile tabes dorsalis, aortitis, and asymptomatic neurosyphilis. [3] Thus highlighting the importance of early screening in pregnant people and neonates, with prompt treatment.
Argyll Robertson pupils were named after Douglas Argyll Robertson (1837–1909), a Scottish ophthalmologist and surgeon who described the condition in the mid-1860s in the context of neurosyphilis. In the early 20th century, William John Adie described a second type of pupil that could "accommodate but not react".
Competition in cancer treatment continues to intensify, potentially challenging Merck's market leadership. At 10.2 times forward earnings, Merck stock trades at a valuation that reflects both its ...
Tabes dorsalis is a late consequence of neurosyphilis, characterized by the slow degeneration (specifically, demyelination) of the neural tracts primarily in the dorsal root ganglia of the spinal cord (nerve root). These patients have lancinating nerve root pain which is aggravated by coughing, and features of sensory ataxia with ocular ...