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Lenalidomide, sold under the brand name Revlimid among others, is a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes (MDS). [8] For multiple myeloma, it is a first line treatment, and is given with dexamethasone . [ 8 ]
The thalidomide molecule is a synthetic derivative of glutamic acid and consists of a glutarimide ring and a phthaloyl ring (Figure 5). [15] [16] Its IUPAC name is 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione and it has one chiral center [15] After thalidomide's selective inhibition of TNF-α had been reported, a renewed effort was put in thalidomide's clinical development.
Tafasitamab, sold under the brand name Monjuvi, is a medication used in combination with lenalidomide for the treatment of adults with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). [5] Tafasitamab may cause serious side effects including infusion related reactions, bone marrow suppression, infections, and harm to an unborn baby. [7]
The pictogram for harmful substances of the Globally Harmonized System of Classification and Labelling of Chemicals.. The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) is an internationally agreed-upon standard managed by the United Nations that was set up to replace the assortment of hazardous material classification and labelling schemes previously used around ...
An example of a HMIS III label for Diesel Fuel.. The Hazardous Materials Identification System (HMIS) is a proprietary numerical hazard rating that incorporates the use of labels with color bars developed by the American Coatings Association as a compliance aid for the OSHA Hazard Communication (HazCom) Standard.
Celgene Corporation is a pharmaceutical company that makes cancer and immunology drugs. Its major product is Revlimid (lenalidomide), which is used in the treatment of multiple myeloma, and also in certain anemias.
The drug lenalidomide contains the substructure glutarimide (blue) Glutarimide is sometimes called 2,6-piperidinedione. It is the core of a variety of drugs , including lenalidomide , a medication used to treat anemia and multiple myeloma ; [ 3 ] and cycloheximide , a potent inhibitor of protein synthesis.
English: Skeletal formulae of lenalidomide (trade name Revlimid) enantiomers. It is an immunomodulatory imide drug (IMiD) approved for the management of multiple myeloma and myelodysplastic syndrome. Created with ChemDoodle 7.0.2 and Adobe Illustrator CC 2015.