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Symptoms classically affect a leg and typically develop over hours or days, [20] though they can develop suddenly or over a matter of weeks. [21] The legs are primarily affected, with 4–10% of DVT occurring in the arms. [11] Despite the signs and symptoms being highly variable, [5] the typical symptoms are pain, swelling, and redness.
Rheumatoid vasculitis may affect almost any organ in the body. The skin and peripheral nerves are the most frequently affected areas. Although major organ system involvement of the kidney, bowel, or heart is much less common, it can result in serious morbidity and mortality, such as renal failure, bowel ischemia, and myocardial infarction. [3]
The disease's symptoms can range from catastrophic neurological impairment to an asymptomatic condition brought on by impalpable pulses or bruits. [7] Non-specific features include mild anemia, myalgia, arthralgia, weight loss, malaise, night sweats, and fever. [8] Giant cell arteritis (GCA) is the most common type of systemic vasculitis in adults.
Vascular disease is a subgroup of cardiovascular disease. Disorders in this vast network of blood and lymph vessels can cause a range of health problems that can sometimes become severe, and fatal. [3] Coronary heart disease for example, is the leading cause of death for men and women in the United States. [5]
Arthritis is a term often used to mean any disorder that affects joints. [2] Symptoms generally include joint pain and stiffness. [2] Other symptoms may include redness, warmth, swelling, and decreased range of motion of the affected joints. [2] [3] In some types of arthritis, other organs are also affected. [7] Onset can be gradual or sudden. [6]
If the impaired vein function causes significant symptoms, such as swelling and ulcer formation, it is referred to as chronic venous disease. [3] It is sometimes called chronic peripheral venous insufficiency and should not be confused with post-thrombotic syndrome in which the deep veins have been damaged by previous deep vein thrombosis .
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Peripheral artery disease most commonly affects the legs, but other arteries may also be involved, such as those of the arms, neck, or kidneys. [4] [17] Peripheral artery disease (PAD) is a form of peripheral vascular disease. Vascular refers to both the arteries and veins within the body.