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Folate deficiency, also known as vitamin B 9 deficiency, is a low level of folate and derivatives in the body. [1] This may result in megaloblastic anemia in which red blood cells become abnormally large, and folate deficiency anemia is the term given for this medical condition. [ 3 ]
Cerebral folate deficiency is a condition in which concentrations of 5-methyltetrahydrofolate are low in the brain as ... Symptoms typically appear at about 5 to 24 ...
Folate deficiency can be caused by unhealthy diets that do not include enough vegetables and other folate-rich foods; diseases in which folates are not well absorbed in the digestive system (such as Crohn's disease or celiac disease); some genetic disorders that affect levels of folate; and certain medicines (such as phenytoin, sulfasalazine ...
Other common causes include diabetes, glandular fever, vitamin B12 and folate deficiency, and hypothyroidism, which is when the thyroid gland doesn’t produce enough thyroid hormone leading to ...
Folate (Vitamin B 9) deficiency: Symptoms may include feeling tired, heart palpitations, shortness of breath, feeling faint, open sores on the tongue, loss of appetite, changes in the color of the skin or hair, irritability, and behavioral changes. [32] In adults, anemia (macrocytic, megaloblastic anemia) can be a sign of advanced folate ...
Macrocytic anemias have several causes but with the implementation of folic acid fortification in North America, folate deficiency has become a rare cause of megaloblastic macrocytic anemia in that part of the world. [1] In this region, Vitamin B 12 deficiency is a far more common cause of megaloblastic macrocytic anemia. [1]
In fact, a severe deficiency in folate can result in a condition called folate-deficiency anemia which has symptoms like hair thinning and pigmentation changes in the hair.
Prolonged deficiency of vitamin B 12 leads to irreversible nervous system damage. HIV-associated vacuolar myelopathy can present with a similar pattern of dorsal column and corticospinal tract demyelination. [citation needed] It has been thought that if someone is deficient in vitamin B 12 and folic acid, the vitamin B 12 deficiency must