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Gout in hands is less common but can happen. In this situation, it usually affects small joints in the fingers. ... If you have untreated gout for a long time, something called tophi can develop ...
Without treatment, episodes of acute gout may develop into chronic gout with destruction of joint surfaces, joint deformity, and painless tophi. [5] These tophi occur in 30% of those who are untreated for five years, often in the helix of the ear, over the olecranon processes, or on the Achilles tendons . [ 5 ]
A tophus (Latin: "stone", pl.: tophi) is a deposit of monosodium urate crystals, in people with longstanding high levels of uric acid (urate) in the blood, a condition known as hyperuricemia. Tophi are pathognomonic for the disease gout. Most people with tophi have had previous attacks of acute arthritis, eventually leading to the formation of ...
Current treatments for hand deformities can be classified by non-surgical or surgical methods. Non-surgical options aim to reduce symptoms and maintain function, such as medicinal treatments like corticosteroids, physical therapy, and splinting. Surgical procedures, however, are rather reserved for extreme cases, but this depends on the ...
Pegloticase (trade name Krystexxa) is a medication for the treatment of severe, treatment-refractory, chronic gout. It is a third line treatment in those in whom other treatments are not effective or are not tolerated. [2] The drug is administered by infusion intravenously. Since October 2023, Amgen Inc. has been the marketer of pegloticase in ...
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