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Reproductive toxicants may adversely affect sexual function, ovarian failure, fertility as well as causing developmental toxicity in the offspring. [ 2 ] [ 3 ] Lowered effective fertility related to reproductive toxicity relates to both male and female effects alike and is reflected in decreased sperm counts, semen quality and ovarian failure.
Reproductive Toxicology is a peer-reviewed journal published bimonthly by Elsevier which focuses on the effects of toxic substances on the reproductive system. The journal was established in 1987 and is affiliated with the European Teratology Society. According to the Journal Citation Reports, the journal has a 2023 impact factor of 3.3. [1]
Developmental toxicity is any developmental malformation that is caused by the toxicity of a chemical or pathogen. It is the structural or functional alteration, reversible or irreversible, which interferes with homeostasis, normal growth, differentiation, development or behavior.
She joined the National Institute of Environmental Health Sciences in September 2009 as a reproductive endocrinologist in the mechanistic toxicology branch. [3] She researched how per- and polyfluoroalkyl substances and other environmental chemicals affect health across the lifespan — from fetal outcomes and mammary gland development to ...
He was elected to two National Academy of Sciences toxicology committees. [8] [9] Dr. Holson is an editor and author of the textbook Regulatory Toxicology [10] and an author of two significant chapters in the textbook Developmental and Reproductive Toxicology: A Practical Approach, Second Edition.
Environmental toxicants and fetal development is the impact of different toxic substances from the environment on the development of the fetus.This article deals with potential adverse effects of environmental toxicants on the prenatal development of both the embryo or fetus, as well as pregnancy complications.
Ovarian culture is an in-vitro process that allows for the investigation of the development, toxicology and pathology of the ovary. [1] This technique can also be used to study possible applications of fertility treatments e.g. isolating oocytes from primordial ovarian follicles that could be used for fertilisation.
Women should speak to their doctor or healthcare professional before starting or stopping any medications while pregnant. [1] Drugs taken in pregnancy including over-the counter-medications, prescription medications, nutritional supplements, recreational drugs, and illicit drugs may cause harm to the mother or the unborn child.
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