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In this affidavit, Bugie stated that she was informed about streptomycin by Waksman and Shatz and had no part in the discovery of streptomycin. [18] Bugie was, however, later quoted by her daughters as having said that if the women's liberation movement had been present, she would have received credit towards the patent on streptomycin. [1]
Schatz was the lead author of the paper on streptomycin discovery with Bugie as the second. Bugie was excluded from the patent due to Waksman's impression that she would "just get married." [16] Years later Bugie told her daughters, "If women's lib had been around, my name would have been on the patent." [34]
In 1944 Albert Schatz, Elizabeth Bugie, and Selman Waksman isolated streptomycin produced by a bacterial strain Streptomyces griseus. Streptomycin was the first effective antibiotic against M. tuberculosis. [113] This discovery is generally considered the beginning of the modern era of tuberculosis. [113]
It is not recommended in people with myasthenia gravis or other neuromuscular disorders. [4] Streptomycin is an aminoglycoside. [3] It works by blocking the ability of 30S ribosomal subunits to make proteins, which results in bacterial death. [3] Albert Schatz first isolated streptomycin in 1943 from Streptomyces griseus.
Selman Abraham Waksman (July 22, 1888 – August 16, 1973) was a Jewish American inventor, Nobel Prize laureate, biochemist and microbiologist whose research into the decomposition of organisms that live in soil enabled the discovery of streptomycin and several other antibiotics.
Wainwright has also written widely about the history of the discovery of penicillin (including that Adolf Hitler’s life was saved by the drug) and streptomycin [7] and on the hypothesis that bacteria and other non-virus microbes cause cancer.
Sign at the side entrance of the Waksman Institute. The Waksman Institute of Microbiology is a research facility on the Busch Campus of Rutgers University.It is named after Selman Waksman, a student and then faculty member at Rutgers who won the Nobel Prize for Medicine in 1952 for research which led to the discovery of streptomycin.
Parke-Davis's team of Dr. Rebstock and her team consisting of John Controulis, Harry Crooks, and Quentin Bartz discovered that greater chemical stability could be achieved through catalytic hydrogenation of streptomycin, and this new compound was named dihydrostreptomycin. This discovery was simultaneously made by a team at Merck & Co.