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  2. Route of administration - Wikipedia

    en.wikipedia.org/wiki/Route_of_administration

    Routes of administration are usually classified by application location (or exposition). The route or course the active substance takes from application location to the location where it has its target effect is usually rather a matter of pharmacokinetics (concerning the processes of uptake, distribution, and elimination of drugs).

  3. Instrumental variables estimation - Wikipedia

    en.wikipedia.org/wiki/Instrumental_variables...

    In statistics, econometrics, epidemiology and related disciplines, the method of instrumental variables (IV) is used to estimate causal relationships when controlled experiments are not feasible or when a treatment is not successfully delivered to every unit in a randomized experiment. [1]

  4. Verification and validation - Wikipedia

    en.wikipedia.org/wiki/Verification_and_validation

    Verification is intended to check that a product, service, or system meets a set of design specifications. [6] [7] In the development phase, verification procedures involve performing special tests to model or simulate a portion, or the entirety, of a product, service, or system, then performing a review or analysis of the modeling results.

  5. Diabetic hypoglycemia - Wikipedia

    en.wikipedia.org/wiki/Diabetic_hypoglycemia

    Unfortunately, damage to the autonomic nervous system in the form of autonomic neuropathy is a common complication of long-standing diabetes (especially type 1 diabetes), so the presence of hypoglycemic unawareness may be a sign of autonomic neuropathy, although the autonomic response to hypoglycemia is already impaired in patients with type 1 ...

  6. Glucose tolerance test - Wikipedia

    en.wikipedia.org/wiki/Glucose_tolerance_test

    The glucose tolerance test was first described in 1923 by Jerome W. Conn. [4]The test was based on the previous work in 1913 by A. T. B. Jacobson in determining that carbohydrate ingestion results in blood glucose fluctuations, [5] and the premise (named the Staub-Traugott Phenomenon after its first observers H. Staub in 1921 and K. Traugott in 1922) that a normal patient fed glucose will ...

  7. Hypoglycemia - Wikipedia

    en.wikipedia.org/wiki/Hypoglycemia

    [3] [2] Diabetes medications, like insulin, sulfonylureas, and biguanides can also be adjusted or stopped to prevent hypoglycemia. [3] [2] Frequent and routine blood glucose testing is recommended. [1] [3] Some may find continuous glucose monitors with insulin pumps to be helpful in the management of diabetes and prevention of hypoglycemia. [3]

  8. Don Johnson shares rare photo with all 5 children on his 75th ...

    www.aol.com/don-johnson-shares-rare-photo...

    Don Johnson is basking in all the family love. The "Miami Vice" star celebrated his 75th birthday with his children, including Dakota Johnson.

  9. Optimal experimental design - Wikipedia

    en.wikipedia.org/wiki/Optimal_experimental_design

    The traditional optimality-criteria are invariants of the information matrix; algebraically, the traditional optimality-criteria are functionals of the eigenvalues of the information matrix. A-optimality ("average" or trace) One criterion is A-optimality, which seeks to minimize the trace of the inverse of the information matrix. This criterion ...