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Cycle (cyc) is a gene in Drosophila melanogaster that encodes the CYCLE protein (CYC). The Cycle gene ( c yc) is expressed in a variety of cell types in a circadian manner. It is involved in controlling both the sleep-wake cycle and circadian regulation of gene expression by promoting transcription in a negative feedback mechanism.
8697 52563 Ensembl ENSG00000094880 ENSMUSG00000024370 UniProt Q9UJX2 Q8BGZ4 RefSeq (mRNA) NM_004661 NM_178347 RefSeq (protein) NP_004652 NP_848124 Location (UCSC) Chr 5: 138.19 – 138.21 Mb Chr 18: 34.76 – 34.78 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cell division cycle 23 homolog (S. cerevisiae), also known as CDC23, is a protein that, in humans, is encoded by the CDC23 ...
CHEK2 regulates cell cycle progression and spindle assembly during mouse oocyte maturation and early embryo development. [ 13 ] [ 14 ] Although CHEK2 is a down stream effector of the ATM kinase that responds primarily to double-strand breaks it can also be activated by ATR (ataxia-telangiectasia and Rad3 related) kinase that responds primarily ...
993 12530 Ensembl ENSG00000164045 ENSMUSG00000032477 UniProt P30304 P48964 RefSeq (mRNA) NM_001789 NM_201567 NM_007658 RefSeq (protein) NP_001780 NP_963861 NP_031684 Location (UCSC) Chr 3: 48.16 – 48.19 Mb Chr 9: 109.7 – 109.72 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse M-phase inducer phosphatase 1 also known as dual specificity phosphatase Cdc25A is a protein that in ...
The enlarged cells that are able to re-enter the cell cycle are prone to DNA damage and experience abnormalities in signaling for repair (NHEJ pathway), eventually leading to a replication failure and a permanent cell-cycle exit. [24] Overall, a consistent correlation between larger cell size and senescence has been established.
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Single-cell sequencing examines the nucleic acid sequence information from individual cells with optimized next-generation sequencing technologies, providing a higher resolution of cellular differences and a better understanding of the function of an individual cell in the context of its microenvironment. [1]
898 12447 Ensembl ENSG00000105173 ENSMUSG00000002068 UniProt P24864 Q61457 RefSeq (mRNA) NM_001238 NM_057182 NM_001322259 NM_001322261 NM_001322262 NM_007633 RefSeq (protein) NP_001229 NP_001309188 NP_001309190 NP_001309191 NP_001309188.1 NP_001309190.1 NP_031659 Location (UCSC) Chr 19: 29.81 – 29.82 Mb Chr 7: 37.8 – 37.81 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse G1/S ...