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  2. Allopurinol - Wikipedia

    en.wikipedia.org/wiki/Allopurinol

    Allopurinol is used to reduce urate formation in conditions where urate deposition has already occurred or is predictable. The specific diseases and conditions where it is used include gouty arthritis, skin tophi, kidney stones, idiopathic gout; uric acid lithiasis; acute uric acid nephropathy; neoplastic disease and myeloproliferative disease with high cell turnover rates, in which high urate ...

  3. Allopurinol hypersensitivity syndrome - Wikipedia

    en.wikipedia.org/wiki/Allopurinol...

    Allopurinol hypersensitivity syndrome (AHS) typically occurs in persons with preexisting kidney failure. [3]: 119 Weeks to months after allopurinol is begun, the patient develops a morbilliform eruption [3]: 119 or, less commonly, develops one of the far more serious and potentially lethal severe cutaneous adverse reactions viz., the DRESS syndrome, Stevens Johnson syndrome, or toxic epidermal ...

  4. Cytokine release syndrome - Wikipedia

    en.wikipedia.org/wiki/Cytokine_release_syndrome

    CRS needs to be distinguished from symptoms of the disease itself and, in the case of drugs, from other adverse effects—for example tumor lysis syndrome requires different interventions. As of 2015, differential diagnoses depended on the judgement of doctor as there were no objective tests. [5]

  5. Tumor lysis syndrome - Wikipedia

    en.wikipedia.org/wiki/Tumor_lysis_syndrome

    Allopurinol (a xanthine oxidase inhibitor, which inhibits uric acid production) works by preventing the formation of uric acid following tumor cell lysis. [4] [13] Rasburicase is a synthetic urate oxidase enzyme and acts by degrading uric acid. No current guidelines endorse the concurrent use of allopurinol and rasburicase.

  6. This disease kills more people than all cancers and accidents ...

    www.aol.com/disease-kills-more-people-cancers...

    The researchers called for interventions to help reduce heart disease risk factors. "Any medical or clinical therapies that can treat the risk factors that contribute to CVD are essential ...

  7. Toxic epidermal necrolysis - Wikipedia

    en.wikipedia.org/wiki/Toxic_epidermal_necrolysis

    The most common cause is certain medications such as lamotrigine, carbamazepine, allopurinol, sulfonamide antibiotics, and nevirapine. [2] Other causes can include infections such as Mycoplasma pneumoniae and cytomegalovirus or the cause may remain unknown. [3] [4] Risk factors include HIV/AIDS and systemic lupus erythematosus. [2]

  8. We know why cats knead. But here's why humans love it so much.

    www.aol.com/know-why-cats-knead-heres-100401607.html

    Kittens knead their mother's mammary glands, or breasts, while nursing, likely to aid the release of milk. Animal experts call this process "milk let down," said Sung, who is based in Walnut Creek ...

  9. We interviewed 40 nurses and they said these are the best ...

    www.aol.com/lifestyle/best-shoes-according-to...

    Sizes available: Women’s sizes 4.5/5 to 12.5/13; men’s sizes 7.5/8 to 14.5/15 | Widths: Narrow, regular, and wide The Dansko Professional is a nursing icon — and the top clog choice among ...