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This is a timeline of influenza, briefly describing major events such as outbreaks, epidemics, pandemics, discoveries and developments of vaccines.In addition to specific year/period-related events, there is the seasonal flu that kills between 250,000 and 500,000 people every year and has claimed between 340 million and 1 billion human lives throughout history.
The vaccine produces a greater immune response than standard vaccine. According to the CDC, [1] "a study published in the New England Journal of Medicine [25] [in August, 2014] indicated that the high-dose vaccine was 24.2% more effective in preventing flu in adults 65 years of age and older relative to a standard-dose vaccine." The CDC ...
This is a timeline of the development of prophylactic human vaccines. Early vaccines may be listed by the first year of development or testing, but later entries usually show the year the vaccine finished trials and became available on the market. Although vaccines exist for the diseases listed below, only smallpox has
Pandemic: It’s a scary word. But the world has seen pandemics before, and worse ones, too. Consider the influenza pandemic of 1918, often referred to erroneously as the “Spanish flu ...
In December 2008, research by Yoshihiro Kawaoka of the University of Wisconsin linked the presence of three specific genes (termed PA, PB1, and PB2) and a nucleoprotein derived from Spanish flu samples to the ability of the 1918 flu virus to invade the lungs and cause pneumonia. These genes were inserted into a modern H1N1 strain and triggered ...
In 1918, the world's population was menaced by a virus now known as influenza. The "flu," for short, has become a commonality that is widely misunderstood, even a century after it claimed 50 ...
1918 Flu: Influenza A/H1N1: 17–100 million 1–5.4% of global population [4] 1918–1920 Worldwide 2 Plague of Justinian: Bubonic plague 15–100 million 25–60% of European population [5] 541–549 North Africa, Europe, and Western Asia 3 HIV/AIDS pandemic: HIV/AIDS: 44 million (as of 2025) – 1981–present [6] Worldwide 4 Black Death ...
The United States and Europe are taking steps to acquire or manufacture H5N1 bird flu vaccines that could be used to protect at-risk poultry and dairy workers, veterinarians and lab technicians ...