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  2. Familial hypercholesterolemia - Wikipedia

    en.wikipedia.org/wiki/Familial_hypercholesterolemia

    Familial hypercholesterolemia (FH) is a genetic disorder characterized by high cholesterol levels, specifically very high levels of low-density lipoprotein cholesterol (LDL cholesterol), in the blood and early cardiovascular diseases. The most common mutations diminish the number of functional LDL receptors in the liver or produce abnormal LDL ...

  3. Prothrombin G20210A - Wikipedia

    en.wikipedia.org/wiki/Prothrombin_G20210A

    Prothrombin G20210A is a genotypic trait that provides a prompter coagulation response. It increases the risk of blood clots including from deep vein thrombosis, and of pulmonary embolism. [1] One copy of the mutation increases the risk of a blood clot from 1 in 1,000 per year to 2.5 in 1,000. [1] Two copies increases the risk to up to 20 in ...

  4. Cardiovascular disease - Wikipedia

    en.wikipedia.org/wiki/Cardiovascular_disease

    Cardiovascular disease (CVD) is any disease involving the heart or blood vessels. [3] CVDs constitute a class of diseases that includes: coronary artery diseases (e.g. angina, heart attack), heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, arrhythmia, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease ...

  5. Cardiomegaly - Wikipedia

    en.wikipedia.org/wiki/Cardiomegaly

    Cardiomegaly (sometimes megacardia or megalocardia) is a medical condition in which the heart becomes enlarged. It is more commonly referred to simply as "having an enlarged heart ". It is usually the result of underlying conditions that make the heart work harder, such as obesity, heart valve disease, high blood pressure (hypertension), and ...

  6. Coronary artery disease - Wikipedia

    en.wikipedia.org/wiki/Coronary_artery_disease

    Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), [13] is a type of heart disease involving the reduction of blood flow to the cardiac muscle due to build-up of atherosclerotic plaque in the arteries of the heart. [5] [6] [14] It is the most common of the cardiovascular diseases. [15]

  7. Angina - Wikipedia

    en.wikipedia.org/wiki/Angina

    Pronunciation. / ænˈdʒaɪnə, ˈændʒɪnə / ann-JY-nə, AN-jin-ə[1] Specialty. Cardiology. Complications. Heart attack, unstable angina. Angina, also known as angina pectoris, is chest pain or pressure, usually caused by insufficient blood flow to the heart muscle (myocardium). [2] It is most commonly a symptom of coronary artery disease.

  8. Hypertrophic cardiomyopathy - Wikipedia

    en.wikipedia.org/wiki/Hypertrophic_cardiomyopathy

    Up to 1 in 200 people [8] Hypertrophic cardiomyopathy (HCM, or HOCM when obstructive) is a condition in which muscle tissues of the heart become thickened without an obvious cause. [8] The parts of the heart most commonly affected are the interventricular septum and the ventricles. [10]

  9. Family history (medicine) - Wikipedia

    en.wikipedia.org/wiki/Family_history_(medicine)

    This is seen particularly in cardiac disease, where strong family history is considered a significant cardiovascular risk factor. [14] In diseases with a known hereditary component, many otherwise healthy people with a positive family history are tested early, with the aim of an early diagnosis and intervention to prevent the symptoms from ...