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  2. Can Gabapentin Really Cause ED? - AOL

    www.aol.com/lifestyle/gabapentin-really-cause-ed...

    Gabapentin could cause ED, desire changes and dysfunction. There’s evidence that gabapentin may affect a man’s ability to reach climax (either by causing PE or delayed climax), especially if ...

  3. Gabapentin - Wikipedia

    en.wikipedia.org/wiki/Gabapentin

    Gabapentin is not a direct calcium channel blocker: it exerts its actions by disrupting the regulatory function of α 2 δ and its interactions with other proteins. Gabapentin reduces delivery of intracellular calcium channels to the cell membrane, reduces the activation of the channels by the α 2 δ subunit, decreases signaling leading to ...

  4. Enalapril - Wikipedia

    en.wikipedia.org/wiki/Enalapril

    Enalapril, sold under the brand name Vasotec among others, is an ACE inhibitor medication used to treat high blood pressure, diabetic kidney disease, and heart failure. [5] For heart failure, it is generally used with a diuretic , such as furosemide . [ 6 ]

  5. What is gabapentin? Here's why it's so controversial. - AOL

    www.aol.com/gabapentin-heres-why-controversial...

    Gabapentin is a prescription medication that was approved by the U.S. Food and Drug Administration in 1993 as a treatment for epilepsy. It works by binding to a type of calcium channel in nerve ...

  6. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    Interactions with other drugs, food and drink, and other factors may increase or decrease the effect of certain analgesics and alter their half-life. Because some listed analgesics are prodrugs or have active metabolites , individual variation in liver enzymes (e.g., CYP2D6 enzyme) may result in significantly altered effects.

  7. ACE inhibitor and thiazide combination - Wikipedia

    en.wikipedia.org/wiki/ACE_inhibitor_and_thiazide...

    The FDA modified its labeling in February 2009 to include a precaution of drug interaction with gold. "Nitritoid reactions (symptoms include facial flushing, nausea, vomiting and hypotension) have been reported rarely in patients on therapy with injectable gold ( sodium aurothiomalate ) and concomitant ACE inhibitor therapy including Monopril ...

  8. Gabapentin enacarbil - Wikipedia

    en.wikipedia.org/wiki/Gabapentin_enacarbil

    Gabapentin enacarbil (Horizant (ER) (U.S. Tooltip United States), Regnite (in Japan)) is an anticonvulsant and analgesic drug of the gabapentinoid class, and a prodrug to gabapentin. [1] It was designed for increased oral bioavailability over gabapentin, [ 2 ] [ 3 ] and human trials showed it to produce extended release of gabapentin with ...

  9. Depressant - Wikipedia

    en.wikipedia.org/wiki/Depressant

    Gabapentin was designed by researchers at Parke-Davis to be an analogue of the neurotransmitter GABA that could more easily cross the blood–brain barrier and was first described in 1975 by Satzinger and Hartenstein. [22] [23] Gabapentin was first approved for epilepsy, mainly as an add-on treatment for partial seizures.

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