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Keratinized surfaces are protected from absorption by keratin protein. Keratinized epithelium has keratin deposited on the surface which makes it impermeable and dry. Examples of keratinized stratified squamous epithelium include skin, the epidermis of the palm of the hand, and the sole of the foot, [3] and the masticatory mucosa.
Keratinized squamous epithelium is present in the gingiva and hard palate as well as areas of the dorsal surface of the tongue. [ 8 ] [ 9 ] Keratinization is the differentiation of keratinocytes in the stratum granulosum into nonvital surface cells or squames to form the stratum corneum.
A similar study was conducted about keratin expression in normal esophageal epithelium and squamous cell carcinoma of the esophagus. To sum it up, the molecular weight was taken of squamous cell carcinoma in the esophagus and normal esophageal epithelium using a immunoblot analysis [ 7 ] The squamous tissue which had keratins weighed more than ...
In structure, it consists of a keratinized stratified squamous epithelium; four types of cells: keratinocytes, melanocytes, Merkel cells, and Langerhans cells. The predominant cell keratinocyte , which produces keratin , a fibrous protein that aids in skin protection, is responsible for the formation of the epidermal water barrier by making and ...
Stratified squamous epithelium: is simulated by oral keratinocytes cultured in a medium containing keratinocyte growth factors such as the epidermal growth factor (EGF). [ 1 ] To obtain the best results, the type and origin of the fibroblasts and keratinocytes used in oral mucosa tissue engineering are important factors to hold into account.
Odontogenic keratocysts have a diagnostic histological appearance. Under the microscope, OKCs vaguely resemble keratinized squamous epithelium; [15] however, they lack rete ridges and often have an artifactual separation from their basement membrane. [2] The fibrous wall of the cyst is usually thin and uninflamed.
Cholesteatoma is a destructive and expanding growth consisting of keratinizing squamous epithelium in the middle ear and/or mastoid process. [1] [2] Cholesteatomas are not cancerous as the name may suggest, but can cause significant problems because of their erosive and expansile properties.
Non-keratinized squamous epithelium, including cornea and transitional epithelium [6] Cytokeratin 7: A subgroup of glandular epithelia and their tumors [6] Transitional epithelium and transitional carcinoma [6] Cytokeratin 8: Glandular epithelia of the digestive, respiratory and urogenital tracts, both endocrine and exocrine cells, as well as ...