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Staying up to date with the latest blood glucose–lowering medications is an important part of diabetes management. Check out our comprehensive chart to understand how your meds work, and keep the list handy for times when your health care provider suggests changes to your treatment plan.
Diabetes treatment: Lowering blood sugar. Several classes of type 2 diabetes medicines exist. Each class of medicine works in a different way to lower blood sugar. A medication may work by: Causing the pancreas to make and release more insulin. Limiting the liver's ability to make and release sugar.
Now, a large clinical trial has compared four different drugs used to control type 2 diabetes and found that two of the drugs did statistically better. However, there wasn’t more than a modest difference between all four of the drugs.
Use this table to look up the different medications that can be used to treat type 2 diabetes. Use the links below to find medications within the table quickly, or click the name of the drug to link to expanded information about the drug.
Comparison Chart of Glucose-Lowering Agents for Management of Type 2 Diabetes Mellitus. Jennifer Allen, PharmD, BCACP, CDE and Sonia Freitas, PharmD, BCACP, CDE October 2015. Abbreviations: a FBG = fasting blood glucose, PPBG = post prandial blood glucose, bSMBG = self-monitoring of blood glucose. References.
Learn about the different classes of non-insulin type 2 diabetes medications used to lower blood glucose levels. Explore options like Metformin, DPP-4 inhibitors, GLP-1, and more.
Diabetes Medication Comparison Table: Benefits and Risks. This chart has been adapted from a 2009 AACE Guidelines chart. Copyright © 2011 Diabetes In Control, Inc.
CompareDiabetesDrugs.com compares the different drugs used to treat type 2 diabetes. It allows comparisons to be made for glycated hemoglobin (HbA1c), weight and risk of hypoglycemia.
Oral Combination Therapy: Because the drugs listed in this chart act in different ways to lower blood glucose levels, providers will often prescribe multiple drugs to a patient, such as both a biguanide and a sulfonylurea.
The table below summarizes the agents available for the treatment of type 2 diabetes, including expected A1c reduction when added to metformin, cost, adverse effects, and other pertinent information (e.g., place in therapy, pediatric use, cardiorenal benefit).