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Reproducibility, closely related to replicability and repeatability, is a major principle underpinning the scientific method.For the findings of a study to be reproducible means that results obtained by an experiment or an observational study or in a statistical analysis of a data set should be achieved again with a high degree of reliability when the study is replicated.
Reproducibility can also be distinguished from replication, as referring to reproducing the same results using the same data set. Reproducibility of this type is why many researchers make their data available to others for testing. [15] The replication crisis does not necessarily mean these fields are unscientific.
Replication in statistics evaluates the consistency of experiment results across different trials to ensure external validity, while repetition measures precision and internal consistency within the same or similar experiments. [5] Replicates Example: Testing a new drug's effect on blood pressure in separate groups on different days.
In addition to the main result, Ioannidis lists six corollaries for factors that can influence the reliability of published research. Research findings in a scientific field are less likely to be true, the smaller the studies conducted. the smaller the effect sizes. the greater the number and the lesser the selection of tested relationships.
After 2005, research integrity has been additionally redefined through the perspective of research reproducibility and, more specifically, of the "reproducibility crisis". Studies of reproducibility suggest that there is continuum between irreproducibility, questionable research practices and scientific misconducts: "Reproducibility is not just ...
Reproducibility crisis and other issues of research transparency have become a public topic addressed in the general press: "Reproducibility conversations are also unique compared to other methodological conversations because they have received sustained attention in both the scientific literature and the popular press".
The Reproducibility Project is a series of crowdsourced collaborations aiming to reproduce published scientific studies, finding high rates of results which could not be replicated. It has resulted in two major initiatives focusing on the fields of psychology [ 1 ] and cancer biology. [ 2 ]
There are different reasons for performing a round-robin test: determination the reproducibility of a test method or process; verification of a new method of analysis. If a new method of analysis has been developed, a round-robin test involving proven methods would verify whether the new method produces results that agree with the established method.