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Medical grade silicones are silicones tested for biocompatibility and are appropriate to be used for medical applications. [1] In the United States, the Food and Drug Administration (FDA) Center for Devices and Radiological Health (CDRH) regulates devices implanted into the body. It does not regulate materials other than certain dental materials.
Silicone rubber is a reliable solution (as opposed to rubber and thermoplastic elastomers) for migration or interaction problems between the main active ingredients. Its chemical stability prevents it from affecting any substrate it is in contact with (skin, water, blood, active ingredients, etc.).
Due to their inert nature, medical-grade Silastic-brand silicone elastomers are important materials in numerous medical and pharmaceutical devices including catheters, pacemaker leads, tubing, wound dressings, silos for abdominal wall defects, [2] and nasolacrimal duct obstruction. [3]
Tygon R-3603 Laboratory Tubing is commonly used in chemical laboratories. It is often used in incubators and as a replacement for rubber tubing for Bunsen burners. This material is produced in vacuum sizes and can withstand a full vacuum at room temperature. It is a thermoplastic PVC-based material with plasticizer. [3]
A range of polymers are used for the construction of catheters, including silicone rubber, nylon, polyurethane, polyethylene terephthalate (PET), latex, and thermoplastic elastomers. Silicone is one of the most common implantable choice because it is inert and unreactive to body fluids and a range of medical fluids with which it might come into ...
The rubbery, vinegary-smelling silicone caulks, adhesives, and aquarium sealants are also well-known. PDMS is also used as a component in silicone grease and other silicone based lubricants , as well as in defoaming agents , mold release agents , damping fluids, heat transfer fluids, polishes, cosmetics , hair conditioners, shining latex , and ...
Injection molding of liquid silicone rubber (LSR) is a process to produce pliable, durable parts in high volume.. Liquid silicone rubber is a high purity platinum cured silicone with low compression set, good stability and ability to resist extreme temperatures of heat and cold ideally suitable for production of parts, where high quality is required.
Most endotracheal tubes today are constructed of polyvinyl chloride, but specialty tubes constructed of silicone rubber, latex rubber, or stainless steel are also widely available. Most tubes have an inflatable cuff to seal the trachea and bronchial tree against air leakage and aspiration of gastric contents, blood, secretions, and other fluids.
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