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  2. Childhood-onset systemic lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Childhood-onset_systemic...

    Childhood-onset systemic lupus erythematosus (i.e., cSLE), also termed juvenile-onset systemic lupus erythematosus, juvenile systemic lupus erythematosus, and pediatric systemic lupus erythematosus, is a form of the chronic inflammatory and autoimmune disease, systemic lupus erythematosus (i.e., SLE), that develops in individuals up to 18 years old. [1]

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  4. Lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Lupus_erythematosus

    Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints , skin , kidneys , blood cells , heart , and lungs .

  5. Lupus - Wikipedia

    en.wikipedia.org/wiki/Lupus

    Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. [1] Symptoms vary among people and may be mild to severe. [ 1 ]

  6. Mariana J. Kaplan - Wikipedia

    en.wikipedia.org/wiki/Mariana_J._Kaplan

    Kaplan's research has focused on identifying mechanisms of immune dysregulation, organ damage, and premature vascular disease in systemic autoimmunity. [1] She investigates how innate immunity (in particular, type I interferons and myeloid cells) promote autoimmune responses and end-organ damage in systemic lupus erythematosus, rheumatoid ...

  7. Autoimmunity - Wikipedia

    en.wikipedia.org/wiki/Autoimmunity

    In this form of the disease, the absence of lymphocytes can accelerate organ damage, and intravenous IgG administration can be therapeutic. Although this route to autoimmune disease may underlie various degenerative disease states, no diagnostics for this disease mechanism exist at present, and thus its role in human autoimmunity is currently ...

  8. Lupus nephritis - Wikipedia

    en.wikipedia.org/wiki/Lupus_nephritis

    Lupus nephritis is an inflammation of the kidneys caused by systemic lupus erythematosus (SLE) and childhood-onset systemic lupus erythematosus which is a more severe form of SLE that develops in children up to 18 years old; both are autoimmune diseases. [3] [4] It is a type of glomerulonephritis in which the glomeruli become inflamed.

  9. McGregor Memorial Conference Center - Wikipedia

    en.wikipedia.org/wiki/McGregor_Memorial...

    The McGregor Memorial Conference Center is a meeting and event facility on the campus of Wayne State University in Midtown Detroit, Michigan, designed by noted Japanese American architect Minoru Yamasaki (1912–1986) and completed in 1958.

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