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Valsartan, sold under the brand name Diovan among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease. [8] It belongs to a class of medications referred to as angiotensin II receptor blockers (ARBs).
The use of valsartan in pregnancy is avoided due to the potential risk of fetal toxicity. [11] The U.S. Food and Drug Administration has a black box warning for valsartan/hydrochlorothiazide use during pregnancy. [2] The use of hydrochlorothiazide is avoided in those with anuria or severe kidney disease. [12]
Iron deficiency anemia in pregnancy can lead to an increased risk of premature delivery, low birth weight and increased risk of perinatal mortality. [ 64 ] The Recommended Dietary Allowance (RDA) suggests 27 mg of iron a day which would account for normal iron losses, iron used by the fetus and related tissues during gestation and increased ...
Individuals with heightened exposure to “forever chemicals” early in pregnancy could be at greater risk of weight gain and heart disease later in life, a new study has found. Those with higher ...
Exposure to those toxins during pregnancy can create serious health issues in elementary school children, a new study found. ... compared with 16% of children within the low-risk group, said first ...
The international pictogram for chemicals that are sensitising, mutagenic, carcinogenic or toxic to reproduction. Reproductive toxicity refers to the potential risk from a given chemical, physical or biologic agent to adversely affect both male and female fertility as well as offspring development. [1]
Losartan, the first ARB. Angiotensin II receptor blockers (ARBs), formally angiotensin II receptor type 1 (AT 1) antagonists, [1] also known as angiotensin receptor blockers, [2] [3] angiotensin II receptor antagonists, or AT 1 receptor antagonists, are a group of pharmaceuticals that bind to and inhibit the angiotensin II receptor type 1 (AT 1) and thereby block the arteriolar contraction and ...
A hazard quotient is the ratio of the potential exposure to a substance and the level at which no adverse effects are expected. If the Hazard Quotient is calculated to be less than 1, then no adverse health effects are expected as a result of exposure. If the Hazard Quotient is greater than 1, then adverse health effects are possible.