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The earliest mention of gene fixation in published works was found in Motoo Kimura's 1962 paper "On Probability of Fixation of Mutant Genes in a Population". In the paper, Kimura uses mathematical techniques to determine the probability of fixation of mutant genes in a population.
Genetic drift is the process by which allele frequencies fluctuate within populations. Natural selection and genetic drift propel evolution forward, and through evolution, alleles can become fixed. [8] [9] Processes of natural selection such as sexual, convergent, divergent, or stabilizing selection pave the way for allele fixation. One way ...
In population genetics, F-statistics (also known as fixation indices) describe the statistically expected level of heterozygosity in a population; more specifically the expected degree of (usually) a reduction in heterozygosity when compared to Hardy–Weinberg expectation.
The probability that A reaches fixation is called fixation probability. For the simple Moran process this probability is x i = i / N . Since all individuals have the same fitness, they also have the same chance of becoming the ancestor of the whole population; this probability is 1 / N and thus the sum of all i probabilities ...
The fixation index (F ST) is a measure of population differentiation due to genetic structure. It is frequently estimated from genetic polymorphism data, such as single-nucleotide polymorphisms (SNP) or microsatellites. Developed as a special case of Wright's F-statistics, it is one of the most commonly used statistics in population genetics ...
Population genetics is a subfield of genetics that deals with genetic differences within and among populations, and is a part of evolutionary biology. Studies in this branch of biology examine such phenomena as adaptation , speciation , and population structure .
Genetic drift, also known as random genetic drift, allelic drift or the Wright effect, [1] is the change in the frequency of an existing gene variant in a population due to random chance. [ 2 ] Genetic drift may cause gene variants to disappear completely and thereby reduce genetic variation . [ 3 ]
In population genetics, extinction probability is the chance of an inherited trait becoming extinct as a function of time t. [1] If t = ∞ this may be the complement of the chance of becoming a universal trait. This opposing process is also known as proceeding to fixation.