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Ceruminous adenocarcinoma is a malignant neoplasm derived from ceruminous glands of the external auditory canal.This tumor is rare, with several names used in the past. [3] [4] Synonyms have included cylindroma, ceruminoma, ceruminous adenocarcinoma, not otherwise specified (NOS), ceruminous adenoid cystic carcinoma (ACC), [1] [2] and ceruminous mucoepidermoid carcinoma.
Whilst hearing loss is a common symptom in many diseases of the ear, for example in otosclerosis (abnormal bone growth in the ear), [3] the white, chalky patches on the tympanic membrane are fairly characteristic of tympanosclerosis. Cholesteatoma is similar in appearance but the whiteness is behind the tympanic membrane, rather than inside.
A ceruminous adenoma is a benign glandular neoplasm which arises from the ceruminous glands located within the external auditory canal. These glands are found within the outer one third to one half of the external auditory canal, more common along the posterior surface; therefore, the tumor develops within a very specific location.
Squamous-cell carcinoma (SCC), also known as epidermoid carcinoma, comprises a number of different types of cancer that begin in squamous cells. [1] These cells form on the surface of the skin, on the lining of hollow organs in the body, and on the lining of the respiratory and digestive tracts .
A hematoxylin and eosin stained intermediate power showing an infiltrating tumor with glandular and neuroendocrine features in a neuroendocrine adenoma of the middle ear. At the time of surgery, the tumor tends to peel away from the adjacent bones, although not the ossicles. It is usually fragmented, soft, rubbery and white to gray-tan.
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Angiofibroma (AGF) is a descriptive term for a wide range of benign skin or mucous membrane (i.e. the outer membrane lining body cavities such as the mouth and nose) lesions in which individuals have:
Clinical history and examination are important. In a significant number of patients there is a familial trait. Examination will white, translucent, slightly raised papules which have a pearly white appearance. Treatment: Any suspicicion of malignant change calls for adequate excision and histological examination.
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