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  2. Alfredo Sadun - Wikipedia

    en.wikipedia.org/wiki/Alfredo_Sadun

    Sadun has focused his research on diseases of the optic nerve, ... Clearing the cornea with nerve growth factor. New England Journal of Medicine, 338(17), 1222–1223.

  3. Nerve growth factor - Wikipedia

    en.wikipedia.org/wiki/Nerve_growth_factor

    4803 18049 Ensembl ENSG00000134259 ENSMUSG00000027859 UniProt P01138 P01139 RefSeq (mRNA) NM_002506 NM_001112698 NM_013609 RefSeq (protein) NP_002497 NP_001106168 NP_038637 Location (UCSC) Chr 1: 115.29 – 115.34 Mb Chr 3: 102.38 – 102.43 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the ...

  4. PAX2 - Wikipedia

    en.wikipedia.org/wiki/PAX2

    Pathologically, Pax2 has been demonstrated to activate hepatocyte growth factor (HGF) gene promoter, and both have been indicated as playing a role in human prostate cancers. [11] Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript ...

  5. SOX10 - Wikipedia

    en.wikipedia.org/wiki/SOX10

    20665 Ensembl ENSG00000100146 ENSMUSG00000033006 UniProt P56693 Q04888 RefSeq (mRNA) NM_006941 NM_011437 RefSeq (protein) NP_008872 NP_035567 Location (UCSC) Chr 22: 37.97 – 37.99 Mb Chr 15: 79.04 – 79.05 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Transcription factor SOX-10 is a protein that in humans is encoded by the SOX10 gene. Function This gene encodes a member of the ...

  6. Development of the nervous system - Wikipedia

    en.wikipedia.org/wiki/Development_of_the_nervous...

    Nerve Growth Factor (NGF): Rita Levi Montalcini and Stanley Cohen purified the first trophic factor, Nerve Growth Factor (NGF), for which they received the Nobel Prize. There are three NGF-related trophic factors: BDNF, NT3, and NT4, which regulate survival of various neuronal populations.

  7. Chemoaffinity hypothesis - Wikipedia

    en.wikipedia.org/wiki/Chemoaffinity_hypothesis

    In follow-up experiments, the eye was detached and rotated 180° like before, but additionally the optic nerve was cut—the results were identical. [ citation needed ] Sperry hypothesized that each individual optic nerve and tectal neuron used some form of chemical marker to dictate the connectivity during development.

  8. Myelinogenesis - Wikipedia

    en.wikipedia.org/wiki/Myelinogenesis

    Furthermore, the use of the rat optic nerve helped provide insight for early myelinogenesis researchers into improper and atypical courses of myelinogenesis. [14] One early study showed that in the developing rat optic nerves, formation of oligodendrocytes and subsequent myelination occurs postnatal. In the optic nerve, the oligodendrocyte ...

  9. GDF10 - Wikipedia

    en.wikipedia.org/wiki/GDF10

    14560 Ensembl ENSG00000266524 ENSMUSG00000021943 UniProt P55107 P97737 RefSeq (mRNA) NM_004962 NM_145741 RefSeq (protein) NP_004953 NP_665684 Location (UCSC) Chr 10: 47.3 – 47.31 Mb Chr 14: 33.65 – 33.66 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Growth differentiation factor 10 (GDF10) also known as bone morphogenetic protein 3B (BMP-3B) is a protein that in humans is ...

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